WO2026044224 - SYNTHETIC PROCESSES FOR PHARMACEUTICALLY ACTIVE COMPOUNDS
National phase entry is expected:
Publication Number
WO/2026/044224
Publication Date
26.02.2026
International Application No.
PCT/US2025/043174
International Filing Date
22.08.2025
Title **
[English]
SYNTHETIC PROCESSES FOR PHARMACEUTICALLY ACTIVE COMPOUNDS
[French]
PROCÉDÉS DE SYNTHÈSE DE COMPOSÉS PHARMACEUTIQUEMENT ACTIFS
Applicants **
AMGEN INC.
Inventors
DOOLEY, III, Charles Joseph
WALKER, Morgan MacKenzie
PARSONS, Andrew T.
Priority Data
63/686,361
23.08.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3055 | |
| EPO | Filing, Examination, Granting | 26012 | |
| Japan | Filing, Examination, Granting | 3233 | |
| South Korea | Filing, Examination, Granting | 4259 | |
| USA | Filing, Examination, Granting | 10740 |
Total:
47,299
Contact Us
Abstract[English]
A process for making a compound of Compound 1 having the following structure: or a salt thereof, said method comprising contacting 2-fluorobenzoic acid (compound 1) with an iron catalyst and a phosphine ligand in the presence of a methylaluminum reagent and 1,2-dichloropropane.[French]
L'invention concerne un procédé de production d'un composé du composé 1 présentant la structure suivante : ou un sel de celui-ci, ledit procédé comprenant la mise en contact de l'acide 2-fluorobenzoïque (composé 1) avec un catalyseur de fer et un ligand de phosphine en présence d'un réactif de méthylaluminium et de 1,2-dichloropropane.