WO2025111449 - METHOD AND REAGENT TO CLEAR TURBIDITY DUE TO ELEVATED TRIGLYCERIDES IN A BIOLOGICAL SPECIMEN

National phase entry is expected:
Publication Number WO/2025/111449
Publication Date 30.05.2025
International Application No. PCT/US2024/056874
International Filing Date 21.11.2024
Title **
[English] METHOD AND REAGENT TO CLEAR TURBIDITY DUE TO ELEVATED TRIGLYCERIDES IN A BIOLOGICAL SPECIMEN
[French] PROCÉDÉ ET RÉACTIF POUR ÉLIMINER LA TURBIDITÉ DUE À DES TRIGLYCÉRIDES ÉLEVÉS DANS UN ÉCHANTILLON BIOLOGIQUE
Applicants **
SUN DIAGNOSTICS, INC.
Inventors
CONTOIS, John
ALBERT, Andre
NGUYEN, Rae-Anne
Priority Data
63/601,403   21.11.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2072
EPO Filing, Examination, Granting11576
Japan Filing, Examination, Granting2124
South Korea Filing, Examination, Granting2071
USA Filing, Examination, Granting4310
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Total: 22,153

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Certain bodily fluid samples include triglyceride-rich lipoproteins. These triglyceride-rich lipoproteins may interfere with analysis to determine the concentration of other components in the bodily fluid samples. A method is disclosed to eliminate or reduce the concentration of the triglyceride-rich lipoproteins so that a more accurate analysis can be achieved. A method may involve mixing the sample with the reagent including magnetic beads attached to a complexing agent for the triglyceride-rich lipoproteins. Then the triglyceride-rich lipoproteins may be magnetically separated from the bodily fluid sample and the bodily fluid sample may be analyzed.[French] Certains échantillons de fluide corporel comprennent des lipoprotéines riches en triglycérides. Ces lipoprotéines riches en triglycérides peuvent interférer avec l'analyse pour déterminer la concentration d'autres composants dans les échantillons de fluide corporel. Un procédé est divulgué pour éliminer ou réduire la concentration des lipoprotéines riches en triglycérides de sorte qu'une analyse plus précise peut être obtenue. Un procédé peut consister à mélanger l'échantillon avec le réactif comprenant des billes magnétiques fixées à un agent complexant pour les lipoprotéines riches en triglycérides. Ensuite, les lipoprotéines riches en triglycérides peuvent être magnétiquement séparées de l'échantillon de fluide corporel et l'échantillon de fluide corporel peut être analysé.