WO2023178169 - COMPOSITIONS AND METHODS FOR TREATING THE PATHOPHYSIOLOGY OF SEVERE VIRAL INFECTION

National phase entry is expected:
Publication Number WO/2023/178169
Publication Date 21.09.2023
International Application No. PCT/US2023/064419
International Filing Date 19.04.2023
Title **
[English] COMPOSITIONS AND METHODS FOR TREATING THE PATHOPHYSIOLOGY OF SEVERE VIRAL INFECTION
[French] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA PATHOPHYSIOLOGIE D'UNE INFECTION VIRALE GRAVE
Applicants **
ANEMOI BIOTECH HOLDINGS, INC.
XU, Jian Qing
MANDELL, Robert
LUBIT, Beverly W.
Inventors
XU, Jian Qing
MANDELL, Robert
LUBIT, Beverly W.
Priority Data
63/320,119   15.03.2022   US
63/371,303   12.08.2022   US
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5318
EPO Filing, Examination, Granting36226
Japan Filing, Examination, Granting3143
South Korea Filing, Examination, Granting4297
USA Filing, Examination, Granting11960
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Total: 60,944

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] According to one aspect the described invention provides a method for reducing damaging effects of a severe virus infection in a susceptible subject comprising administering a pharmaceutical composition comprising a vehicle and a recombinant bifunctional fusion protein comprising a recombinant biologically active immunomodulatory component operatively linked to a recombinant biologically active anti-viral component, the recombinant immunomodulatory component comprising a recombinant biologically active human trefoil protein molecule, fragment or variant and the recombinant anti-viral component comprising a recombinant biologically active human interferon molecule, fragment or variant, wherein the method rescues symptoms of the severe virus infection.[French] Selon un aspect, l'invention décrite concerne une méthode de réduction des effets néfastes d'une infection virale grave chez un sujet sensible comprenant l'administration d'une composition pharmaceutique comprenant un véhicule et une protéine de fusion bifonctionnelle recombinante comprenant un composant immunomodulateur biologiquement actif recombinant lié de manière fonctionnelle à un composant antiviral biologiquement actif recombinant, le composant immunomodulateur recombinant comprenant une molécule, un fragment ou une variante de protéine en trèfle humaine biologiquement active recombinante et le composant antiviral recombinant comprenant une molécule, un fragment ou une variante d'interféron humain biologiquement actif recombinant, ladite méthode soulageant les symptômes de l'infection virale grave.