WO2023063932 - CONTINUOUS FLOW, HIGH THROUGHPUT APPARATUS AND METHOD FOR INACTIVATING VIRUSES AND PATHOGENS IN HUMAN PLASMA
National phase entry:
Publication Number
WO/2023/063932
Publication Date
20.04.2023
International Application No.
PCT/US2021/054613
International Filing Date
12.10.2021
Title **
[English]
CONTINUOUS FLOW, HIGH THROUGHPUT APPARATUS AND METHOD FOR INACTIVATING VIRUSES AND PATHOGENS IN HUMAN PLASMA
[French]
APPAREIL À ÉCOULEMENT CONTINU À HAUT DÉBIT ET MÉTHODE D'INACTIVATION DE VIRUS ET D'AGENTS PATHOGÈNES DANS LE PLASMA HUMAIN
Applicants **
CASTOR, Trevor P.
Inventors
CASTOR, Trevor Percival
Priority Data
63/090,701
12.10.2021
US
Application details
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International Searching Authority |
USPTO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Natural Person
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2392 | |
| EPO | Filing, Examination, Granting | 10797 | |
| Japan | Filing, Examination, Granting | 2307 | |
| South Korea | Filing, Examination, Granting | 2463 | |
| USA | Filing, Examination, Granting | 4310 |
Total:
22,269
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention is for a continuous-flow pathogen reduction apparatus and method, based purely on pathogen inactivation physical principles, for controlling or eliminating trans fusion-transmittable infections from emerging pathogens, pandemic viruses, and bioterrorism threats. The invention inactivates both nonenveloped and enveloped viruses as well as pathogenic bacteria and parasites in human plasma and biologies, while retaining the natural bioactivity, integrity and potency of the treated biologic. The method uses critic al, near-critical or supercritical fluids for viral and pathogen reduction of plasma and biologies. The apparatus is designed to rapidly process high volumes of plasma and biologies with high levels of pathogen reduction in a continuous flow fashion.[French]
La présente invention concerne un appareil et une méthodes de réduction d'agents pathogènes à écoulement continu, basés uniquement sur des principes physiques d'inactivation d'agents pathogènes, pour la lutte contre des infections transmissibles par transfusion, ou l'élimination de ces dernières, causées par des agents pathogènes émergents, des virus pandémiques et des menaces bioterroristes. L'invention inactive à la fois des virus non enveloppés et enveloppés ainsi que des bactéries pathogènes et des parasites dans le plasma et des substances biologiques, tout en conservant la bioactivité, l'intégrité et la puissance naturelles de la substance biologique traitée. la méthode utilise des fluides critiques, quasi-critiques ou supercritiques pour la réduction virale et pathogène du plasma et des substances biologiques. L'appareil est conçu pour traiter rapidement des volumes élevés de plasma et de substances biologiques avec des niveaux élevés de réduction d'agents pathogènes en écoulement continu.