WO2024003929 - PROCESS FOR THE PREPARATION OF TUCATINIB

National phase entry:
Publication Number WO/2024/003929
Publication Date 04.01.2024
International Application No. PCT/IN2023/050319
International Filing Date 31.03.2023
Title **
[English] PROCESS FOR THE PREPARATION OF TUCATINIB
[French] PROCÉDÉ DE PRÉPARATION DE TUCATINIB
Applicants **
DR REDDYS LABORATORIES
Inventors
BUDHDEV, Rajeev Rehani
NARIYAM MUNASWAMY, Sekhar
SAMANTA, Pradip Kumar
VASAM, Sridhar
CHIKKAM, Subbarao
Priority Data
202241037014   28.06.2022   IN
202241049619   30.08.2022   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2155
EPO Filing, Examination, Granting11576
Japan Filing, Examination, Granting2155
South Korea Filing, Examination, Granting2170
USA Filing, Examination, Granting5340
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Total: 23,396

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present application relates to process for the preparation of Tucatinib. The present application also relates to the process for the preparation of Tucatinib intermediates. The present application also provides a process for the preparation of amorphous tucatinib. The present application also provides tucatinib triflate salt characterized by PXRD peaks.[French] La présente invention concerne un procédé de préparation de tucatinib. La présente invention concerne également le procédé de préparation d'intermédiaires de tucatinib. La présente invention concerne par ailleurs un procédé de préparation de tucatinib amorphe. La présente invention concerne en outre un sel triflate de tucatinib caractérisé par des pics de DRXP.