WO2026139844 - AROMATIC CARBOXAMIDE COMPOUNDS AND METHODS OF USING THEREOF

National phase entry is expected:
Publication Number WO/2026/139844
Publication Date 02.07.2026
International Application No. PCT/IB2025/063307
International Filing Date 22.12.2025
Title **
[English] AROMATIC CARBOXAMIDE COMPOUNDS AND METHODS OF USING THEREOF
[French] COMPOSÉS CARBOXAMIDES AROMATIQUES ET MÉTHODES D'UTILISATION DE CEUX-CI
Applicants **
NOVARTIS AG
Inventors
BEHNKE, Dirk
BUSSENAULT, Alex
D'ALESSANDRO, Pier Luca
DOUMAMPOUOM-METOUL, Lionel
FISCHER, Christian
FURET, Pascal
JEULIN, Ingrid Karen Jennifer
MACKAY, Angela Claire
MARCHAND, Jean-Rémy Thierry
PATORA-KOMISARSKA, Krystyna
SPANKA, Carsten Alfred Werner
STAUFFER, Frédéric
VON MATT, Peter Josef
Priority Data
63/738,637   24.12.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3310
EPO Filing, Examination, Granting20268
Japan Filing, Examination, Granting2724
South Korea Filing, Examination, Granting3319
USA Filing, Examination, Granting8590
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Total: 38,211
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Abstract[English] The present disclosure relates to compound of Formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, stereoisomer, or tautomer thereof, wherein the variable are as defined herein. The invention further provides modulators or inhibitors of STAT6 activity, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by IL-4 and/or IL-13.[French] La présente divulgation concerne un composé de Formule I (I) ou un sel, hydrate, solvate, stéréoisomère ou tautomère pharmaceutiquement acceptable de celui-ci, les variables étant telles que définies dans la présente. L'invention concerne en outre des modulateurs ou inhibiteurs de l'activité de STAT6, des procédés pour leur préparation, des compositions pharmaceutiques et des médicaments les contenant, ainsi que leur utilisation dans des maladies et troubles médiés par IL-4 et/ou IL-13.