WO2026133284 - METHODS OF EXPANDING AND PRODUCTION OF GAMMADELTA T CELLS

National phase entry is expected:
Publication Number WO/2026/133284
Publication Date 25.06.2026
International Application No. PCT/IB2025/063258
International Filing Date 19.12.2025
Title **
[English] METHODS OF EXPANDING AND PRODUCTION OF GAMMADELTA T CELLS
[French] MÉTHODES D'EXPANSION ET DE PRODUCTION DE LYMPHOCYTES T GAMMA-DELTA
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
BOTHUN, Alisha
GU, Gary
DONG, Tianhan
WANG, Dandan
SOBHANA, Nandhu
Priority Data
63/736,185   19.12.2024   US
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3265
EPO Filing, Examination, Granting27878
Japan Filing, Examination, Granting3323
South Korea Filing, Examination, Granting4641
USA Filing, Examination, Granting12540
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Total: 51,647
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Abstract[English] The present disclosure relates to expanding and production of gamma delta (γδ) T cells, e.g., Vδ1+ γδ T cells. In particular, the present disclosure provides improved methods and processes for activating and expanding γδ T cells (e.g., Vδ1+ γδ T cells) using combined CD3 and CD30 agonists and cytokines.[French] La présente divulgation concerne l'expansion et la production de lymphocytes T gamma-delta (γδ), par exemple des lymphocytes T γδ Vδ1+. En particulier, la présente divulgation fournit des méthodes et des procédés améliorés pour activer et développer des lymphocytes T γδ (par exemple, des lymphocytes T γδ Vδ1+) en utilisant des agonistes combinés de CD3 et CD30 et des cytokines.