WO2026110042 - METHODS OF EXPANSION OF SKIN VDELTA1+ GAMMADELTA T CELLS AND USE OF SAME

National phase entry is expected:
Publication Number WO/2026/110042
Publication Date 28.05.2026
International Application No. PCT/IB2025/061816
International Filing Date 19.11.2025
Title **
[English] METHODS OF EXPANSION OF SKIN VDELTA1+ GAMMADELTA T CELLS AND USE OF SAME
[French] PROCÉDÉS D'EXPANSION DE LYMPHOCYTES T VDELTA1+ GAMMADELTA DE LA PEAU ET LEUR UTILISATION
Applicants **
KING'S COLLEGE LONDON
Inventors
HAYDAY, Adrian
KAMDAR, Shraddha
DAVIES, Daniel
ZLATAREVA, Iva
Priority Data
63/722,540   19.11.2024   US
63/827,068   20.06.2025   US
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3352
EPO Filing, Examination, Granting20648
Japan Filing, Examination, Granting2738
South Korea Filing, Examination, Granting3298
USA Filing, Examination, Granting10990
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Total: 41,026
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Abstract[English] The present disclosure relates to the expansion of gamma delta (γδ) T cells, e.g., Vδ1+ γδ T cells. In particular, the present disclosure provides improved methods and processes for expanding highly active γδ T cells (e.g., Vδ1+ γδ T cells) from skin with the addition of one or more cytokines, such as IL-2, IL-15, and TGF-β.[French] La présente divulgation concerne l'expansion de lymphocytes T gamma delta (γδ), par exemple, des lymphocytes T Vδ1+ γδ. En particulier, la présente divulgation concerne des procédés et des traitements améliorés pour l'expansion de lymphocytes T γδ hautement actifs (par exemple, des lymphocytes T Vδ1+ γδ) à partir de la peau avec l'ajout d'une ou de plusieurs cytokines, telles que l'IL-2, l'IL-15 et le TGF-β.