WO2026053136 - A PROCESS FOR THE PREPARATION OF SOLID FORMS OF (6R)-6-(2-(N-(4-(2-(ETHYLAMINO) ETHYL) BENZYL)-N-ETHYLAMINO)-4-METHOXYPHENYL)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL DIHYDROCHLORIDE

National phase entry is expected:
Publication Number WO/2026/053136
Publication Date 12.03.2026
International Application No. PCT/IB2025/058900
International Filing Date 04.09.2025
Title **
[English] A PROCESS FOR THE PREPARATION OF SOLID FORMS OF (6R)-6-(2-(N-(4-(2-(ETHYLAMINO) ETHYL) BENZYL)-N-ETHYLAMINO)-4-METHOXYPHENYL)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL DIHYDROCHLORIDE
[French] PROCÉDÉ DE PRÉPARATION DE FORMES SOLIDES DE DICHLORHYDRATE DE (6R)-6-(2-(N-(4-(2-(ÉTHYLAMINO)ÉTHYL)BENZYL)-N-ÉTHYLAMINO)-4-MÉTHOXYPHÉNYL)-5,6,7,8-TÉTRAHYDRONAPHTALÉN-2-OL
Applicants **
BIOPHORE INDIA PHARMACEUTICALS PVT. LTD
Inventors
PULLAGURLA, Manik Reddy
PITTA, Bhaskar Reddy
BOGE, Rajesham
RANGISETTY, Jagadeesh Babu
Priority Data
202441066860   04.09.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1956
EPO Filing, Examination, Granting11576
Japan Filing, Examination, Granting2001
South Korea Filing, Examination, Granting1805
USA Filing, Examination, Granting5340
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Total: 22,678
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Abstract[English] The present invention relates to a process for the preparation of solid-state forms of (6R)- 6-(2-(N-(4-(2-(ethylamino)ethyl)benzyl)-N-ethylamino)-4-methoxyphenyl) 5,6,7,8- tetrahydr -onaphthalen-2-ol dihydrochloride (1). Formula (1) Elacestrant dlhydrochloride (1)[French] La présente invention concerne un procédé de préparation de formes à l'état solide de dichlorhydrate de (6R)-6-(2-(N-(4-(2-(éthylamino)éthyl)benzyl)-N-éthylamino)-4-méthoxyphényl)5,6,7,8-tétrahydronaphtalén-2-ol (1). Formule (1) dichlorhydrate d'élacestrant (1)