WO2026003749 - 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CYCLIN-DEPENDENT KINASE INHIBITORS USEFUL FOR THE TREATMENT OF CANCER
National phase entry is expected:
Publication Number
WO/2026/003749
Publication Date
02.01.2026
International Application No.
PCT/IB2025/056453
International Filing Date
25.06.2025
Title **
[English]
7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CYCLIN-DEPENDENT KINASE INHIBITORS USEFUL FOR THE TREATMENT OF CANCER
[French]
DÉRIVÉS DE 7H-PYRROLO[2,3-D]PYRIMIDINE UTILISÉS EN TANT QU'INHIBITEURS DE KINASE DÉPENDANTE DE LA CYCLINE UTILES POUR LE TRAITEMENT DU CANCER
Applicants **
NOVARTIS AG
Inventors
BRINER, Karin
CHEN, Xin
GAO, Xiang
JOSEPH, Sajan
PFISTER, Keith Bruce
RAUNIYAR, Vivek
SMITH, Troy Douglas
WU, Xiaoyun
YUAN, Jun
ZECRI, Frédéric
Priority Data
24185170.8
27.06.2024
EP
25152477.3
17.01.2025
EP
25180265.8
02.06.2025
EP
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 6242 | |
| EPO | Filing, Examination, Granting | 79802 | |
| Japan | Filing, Examination, Granting | 4347 | |
| South Korea | Filing, Examination, Granting | 6601 | |
| USA | Filing, Examination, Granting | 47790 |
Total:
144,782
Contact Us
Abstract[English]
The invention relates to compounds which inhibit Cyclin-Dependent Kinases such as CDK2 (Cyclin-Dependent Kinase 2 or Cell Division protein Kinase 2) and CDK4 (Cyclin-Dependent Kinase 4 or Cell Division protein Kinase 4), and to processes for the preparation of said compounds, pharmaceutical compositions comprising said compounds, and use of said compounds in the treatment of conditions, diseases and disorders mediated by CDK2 and/or CDK4.[French]
L'invention concerne des composés qui inhibent les kinases dépendantes des cyclines telles que CDK2 (kinase dépendante de la cycline 2 ou la protéine kinase 2 de division cellulaire) et CDK4 (kinase dépendante de la cycline 4 ou la protéine kinase 4 de division cellulaire), et des procédés de préparation desdits composés, des compositions pharmaceutiques comprenant lesdits composés, et l'utilisation desdits composés dans le traitement d'états, de maladies et de troubles médiés par CDK2 et/ou CDK4.