WO2026003694 - METHODS OF ENVELOPED VIRUS TRANSDUCTION
National phase entry is expected:
Publication Number
WO/2026/003694
Publication Date
02.01.2026
International Application No.
PCT/IB2025/056366
International Filing Date
24.06.2025
Title **
[English]
METHODS OF ENVELOPED VIRUS TRANSDUCTION
[French]
PROCÉDÉS DE TRANSDUCTION DE VIRUS ENVELOPPÉS
Applicants **
CSL BEHRING LLC
Inventors
KENNEDY, Jarrod J.
GILLE, Andreas
Priority Data
63/663,530
24.06.2024
US
Application details
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International Searching Authority |
USPTO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3771 | |
| EPO | Filing, Examination, Granting | 37668 | |
| Japan | Filing, Examination, Granting | 3388 | |
| South Korea | Filing, Examination, Granting | 4781 | |
| USA | Filing, Examination, Granting | 13710 |
Total:
63,318
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Abstract[English]
The present disclosure relates generally to the manufacturing of gene therapy products, and specifically to methods of transducing a cell with an enveloped virus in a cell culture, methods of increasing an enveloped virus transduction efficiency of a cell in a cell culture and/or methods of increasing potency of an enveloped virus during transduction of a cell in a cell culture, the method contacting a plurality of cells in a cell culture medium with the enveloped virus and a transduction enhancer of Formula (I) or a stereoisomer, a racemate, a pharmaceutically acceptable salt or a solvate thereof.[French]
La présente invention concerne de manière générale la fabrication de produits de thérapie génique, et spécifiquement des procédés de transduction d'une cellule avec un virus enveloppé dans une culture cellulaire, des procédés d'augmentation d'une efficacité de transduction de virus enveloppé d'une cellule dans une culture cellulaire et/ou des procédés d'augmentation de la puissance d'un virus enveloppé pendant la transduction d'une cellule dans une culture cellulaire, le procédé mettant en contact une pluralité de cellules dans un milieu de culture cellulaire avec le virus enveloppé et un activateur de transduction de formule (I) ou un stéréoisomère, un racémate, un sel pharmaceutiquement acceptable ou un solvate associé.