WO2025219956 - COMPOSITIONS AND METHODS FOR RNA DELIVERY TO CELLS
National phase entry is expected:
Publication Number
WO/2025/219956
Publication Date
23.10.2025
International Application No.
PCT/IB2025/054089
International Filing Date
18.04.2025
Title **
[English]
COMPOSITIONS AND METHODS FOR RNA DELIVERY TO CELLS
[French]
COMPOSITIONS ET PROCÉDÉS POUR UNE ADMINISTRATION D'ARN À DES CELLULES
Applicants **
COMED THERAPEUTICS LTD.
Inventors
ÖZTÜRK, Cenk
HEKIM, Suleyman Nezih
Priority Data
63/635,707
18.04.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3481 | |
| EPO | Filing, Examination, Granting | 26996 | |
| Japan | Filing, Examination, Granting | 3173 | |
| South Korea | Filing, Examination, Granting | 4146 | |
| USA | Filing, Examination, Granting | 11990 |
Total:
49,786
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Abstract[English]
Provided are molecular hooks that are capable of tethering a ribonucleic acid (RNA) of interest to a high-density lipoprotein (HDL) molecule. Also provided are methods of RNA delivery to cells and organisms using the molecular hooks of the present disclosure. Such methods provide several advantages including the ability to deliver the RNA of interest to tissues behind the blood-brain barrier, and not requiring extreme cold temperatures for storage or transport.[French]
L'invention concerne des crochets moléculaires qui sont capables de fixer un acide ribonucléique (ARN) d'intérêt à une molécule de lipoprotéine haute densité (HDL). L'invention concerne également des procédés d'administration d'ARN à des cellules et des organismes utilisant des crochets moléculaires de la présente invention. De tels procédés fournissent plusieurs avantages comprenant la capacité d'administrer l'ARN d'intérêt à des tissus derrière la barrière hémato-encéphalique, et ne nécessitant pas de températures froides extrêmes pour le stockage ou le transport.