WO2025134050 - TRISPECIFIC ANTIBODY TARGETING BCMA, GPRC5D AND CD3 FOR THE TREATMENT OF MULTIPLE MYELOMA

National phase entry is expected:
Publication Number WO/2025/134050
Publication Date 26.06.2025
International Application No. PCT/IB2024/063022
International Filing Date 20.12.2024
Title **
[English] TRISPECIFIC ANTIBODY TARGETING BCMA, GPRC5D AND CD3 FOR THE TREATMENT OF MULTIPLE MYELOMA
[French] ANTICORPS TRISPÉCIFIQUE CIBLANT BCMA, GPRC5D ET CD3 POUR LE TRAITEMENT DU MYÉLOME MULTIPLE
Applicants **
JANSSEN BIOTECH, INC
Inventors
LEE, Sangmin
GOLDBERG, Jenna
SMIT, Marie-Anne Damiette
DASKALAKIS, Nikki
WEIDMAN, Joseph Warren
NGUYEN, Ashley
KREVVATA, Maria
HUTNICK, Natalie
DEANGELIS, Nikki Alaina
ELSAYED, Yusri Ali
Priority Data
63/613,454   21.12.2023   US
63/660,768   17.06.2024   US
63/695,975   18.09.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting7034
EPO Filing, Examination, Granting100505
Japan Filing, Examination, Granting4787
South Korea Filing, Examination, Granting7570
USA Filing, Examination, Granting23990
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Total: 143,886

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Embodiments of the present disclosure relate to methods of treating multiple myeloma in a subject in need thereof, comprising administering a therapeutically effective amount of a BCMA x GPRC5D x CD3 trispecific antibody or trispecific binding fragment thereof, to the subject to the subject to treat the multiple myeloma.[French] Des modes de réalisation de la présente divulgation concernent des méthodes de traitement du myélome multiple chez un sujet en ayant besoin, comprenant l'administration d'une quantité thérapeutiquement efficace d'un anticorps trispécifique ciblant BCMA x GPRC5D x CD3 ou d'un fragment de liaison trispécifique de celui-ci au sujet pour traiter le myélome multiple.