WO2025109567 - FORMULATIONS OF LIPID NANO EMULSIONS WITH CONTROLLED PHARMACOKINETIC PROFILES AND METHODS OF MAKING AND USING THE SAME

National phase entry is expected:
Publication Number WO/2025/109567
Publication Date 30.05.2025
International Application No. PCT/IB2024/061861
International Filing Date 26.11.2024
Title **
[English] FORMULATIONS OF LIPID NANO EMULSIONS WITH CONTROLLED PHARMACOKINETIC PROFILES AND METHODS OF MAKING AND USING THE SAME
[French] FORMULATIONS DE NANO-ÉMULSIONS LIPIDIQUES À PROFILS PHARMACOCINÉTIQUES CONTRÔLÉS ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Applicants **
CERECIN AUSTRALIA PTY LIMITED
Inventors
LIU, Aikun Julie
KAASGAARD, Thomas
Priority Data
63/602,622   26.11.2023   US
63/608,271   10.12.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3775
EPO Filing, Examination, Granting40987
Japan Filing, Examination, Granting3480
South Korea Filing, Examination, Granting5013
USA Filing, Examination, Granting18940
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Total: 72,195

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Provided herein are emulsion composition comprising a medium chain triglyceride (MCT), preferably tricaprilin. Also, described here are additional ingredients that make these emulsion compositions more suitable for oral intake, such as one or more emulsifiers, buffers such as phosphate buffers, as well as optionally glycerol and a sweetener and/or a flavoring agent. Described herein are methods of making and using these emulsions. The emulsions described may be used for oral administration of tricaprilin to treat and/or prevent various diseases or disorders.[French] L'invention concerne une composition d'émulsion comprenant un triglycéride à chaîne moyenne (MCT), de préférence de la tricapriline. Sont également décrits selon la présente invention des ingrédients supplémentaires qui rendent ces compositions d'émulsion plus appropriées pour une administration orale, tels qu'un ou plusieurs émulsifiants, tampons tels que des tampons phosphates, ainsi que facultativement du glycérol et un édulcorant et/ou un agent aromatisant. L'invention concerne des procédés de fabrication et d'utilisation de ces émulsions. Les émulsions décrites peuvent être utilisées pour l'administration orale de tricapriline pour traiter et/ou prévenir diverses maladies ou troubles.