WO2024257013 - BIOMARKERS AND METHODS FOR TREATMENT WITH NAE INHIBITORS

National phase entry is expected:
Publication Number WO/2024/257013
Publication Date 19.12.2024
International Application No. PCT/IB2024/055802
International Filing Date 13.06.2024
Title **
[English] BIOMARKERS AND METHODS FOR TREATMENT WITH NAE INHIBITORS
[French] BIOMARQUEURS ET MÉTHODES DE TRAITEMENT AVEC DES INHIBITEURS DE NAE
Applicants **
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventors
YEH, Tammie
RAMESH, Radha
Priority Data
63/508,842   16.06.2023   US
63/599,169   15.11.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5397
EPO Filing, Examination, Granting113964
Japan Filing, Examination, Granting4598
South Korea Filing, Examination, Granting8743
USA Filing, Examination, Granting30190
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Total: 162,892

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Disclosed herein are markers whose mutational status is associated with sensitivity to treatment with NAE inhibitors. Mutational status is determined by measurement of characteristics of markers corresponding to the marker genes. Compositions and methods are provided to assess markers of marker genes to predict response to NAE inhibition treatment.[French] L'invention concerne des marqueurs dont l'état mutationnel est associé à la sensibilité au traitement par des inhibiteurs de NAE. L'état mutationnel est déterminé par la mesure de caractéristiques de marqueurs correspondant aux gènes marqueurs. L'invention concerne des compositions et des procédés pour évaluer des marqueurs de gènes marqueurs pour prédire une réponse à un traitement d'inhibition de NAE.