WO2024110905 - ANTI-CEA ANTIBODY DRUG CONJUGATES AND METHODS OF USE

National phase entry:
Publication Number WO/2024/110905
Publication Date 30.05.2024
International Application No. PCT/IB2023/061813
International Filing Date 22.11.2023
Title **
[English] ANTI-CEA ANTIBODY DRUG CONJUGATES AND METHODS OF USE
[French] CONJUGUÉS ANTICORPS ANTI-CEA-MÉDICAMENT ET PROCÉDÉS D'UTILISATION
Applicants **
BEIGENE GUANGZHOU BIOLOGICS MANUFACTURING CO., LTD.
BEIGENE SWITZERLAND GMBH
Inventors
TSAI, Charng-Sheng
TSAI, Mei-Hsuan
QU, Liang
WEI, Xiaodong
WANG, Zewei
LUO, Wei
HE, Maomao
LI, Zhuo
Priority Data
PCT/CN2022/134067   24.11.2022   CN
PCT/CN2023/107003   12.07.2023   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4355
EPO Filing, Examination, Granting25206
Japan Filing, Examination, Granting2772
South Korea Filing, Examination, Granting3362
USA Filing, Examination, Granting11940
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Total: 47,635

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure provides antibody drug conjugates comprising antibodies and antigen-binding fragments thereof that bind to human CEA and a linker-payload, a pharmaceutical composition comprising the anti-CEA antibody drug conjugate, and use of the anti-CEA antibody drug conjugate for treating a CEA-related diseases or disorders.[French] La présente invention concerne des conjugués anticorps-médicament comprenant des anticorps et des fragments de liaison à l'antigène de ceux-ci qui se lient au CEA humain et une charge utile de lieur, une composition pharmaceutique comprenant le conjugué anticorps anti-CEA-médicament, et l'utilisation du conjugué anticorps anti-CEA-médicament pour traiter des maladies ou des troubles liés au CEA.