WO2023209692 - INHIBITORS OF ROCK2

National phase entry:
Publication Number WO/2023/209692
Publication Date 02.11.2023
International Application No. PCT/IB2023/054494
International Filing Date 29.04.2023
Title **
[English] INHIBITORS OF ROCK2
[French] INHIBITEURS DE ROCK2
Applicants **
GRAVITON BIOSCIENCE BV
Inventors
WAKSAL, Samuel D.
ZANIN-ZHOROV, Alexandra
KACHKOVSKYI, Georgiy
SOLUCH, Magdalena
JĘDRZEJCZAK, Anna
KLVAŇA, Martin
DOMAGAŁA, Dominik
Priority Data
63/336,667   29.04.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2619
EPO Filing, Examination, Granting13980
Japan Filing, Examination, Granting2502
South Korea Filing, Examination, Granting2754
USA Filing, Examination, Granting5340
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Total: 27,195

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present disclosure relates to inhibitors of Rho-associated protein kinase (ROCK), pharmaceutical compositions comprising the same, and use thereof for the prevention or treatment of a disease mediated by the ROCK. Particularly, the inhibitors of ROCK are selective for the inhibition of ROCK2.[French] La présente divulgation concerne des inhibiteurs de la protéine kinase associée à Rho (ROCK), des compositions pharmaceutiques les comprenant, et leur utilisation pour la prévention ou le traitement d'une maladie médiée par la ROCK. En particulier, les inhibiteurs de ROCK sont sélectifs pour l'inhibition de ROCK2.