WO2023161873 - GENE EDITING REPORTER SYSTEM AND GUIDE RNA AND COMPOSITION RELATED THERETO; COMPOSITION AND METHOD FOR KNOCKING OUT DNA WITH MORE THAN TWO GRNAS; GENE EDITING IN THE EYE; AND GENE EDITING USING BASE EDITORS
National phase entry:
Publication Number
WO/2023/161873
Publication Date
31.08.2023
International Application No.
PCT/IB2023/051742
International Filing Date
24.02.2023
Title **
[English]
GENE EDITING REPORTER SYSTEM AND GUIDE RNA AND COMPOSITION RELATED THERETO; COMPOSITION AND METHOD FOR KNOCKING OUT DNA WITH MORE THAN TWO GRNAS; GENE EDITING IN THE EYE; AND GENE EDITING USING BASE EDITORS
[French]
SYSTÈME RAPPORTEUR D'ÉDITION GÉNIQUE ET ARN GUIDE ET COMPOSITION ASSOCIÉE ; COMPOSITION ET PROCÉDÉ POUR ÉLIMINER L'ADN AVEC PLUS DE DEUX ARNG ; ÉDITION GÉNIQUE DANS L'ŒIL ; ET ÉDITION GÉNIQUE UTILISANT DES ÉDITEURS DE BASES
Applicants **
INCISIVE GENETICS, INC.
THE UNIVERSITY OF BRITISH COLUMBIA
Inventors
LEAVITT, Blair
HILL, Austin
WAGNER, Pamela
SIMPSON, Elizabeth
MOHANNA, Zeinab
ADAIR, Bethany
Priority Data
63/314,044
25.02.2022
US
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CIPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3983 | |
| EPO | Filing, Examination, Granting | 29321 | |
| Japan | Filing, Examination, Granting | 2955 | |
| South Korea | Filing, Examination, Granting | 3854 | |
| USA | Filing, Examination, Granting | 17640 |
Total:
57,753
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present disclosure provides: reporter systems for CRISPR-mediated gene editing; gRNAs, RNPs, and compositions for the reporter systems; and methods of testing CRISPR-mediated gene editing. The present disclosure further provides compositions and methods for knocking out a DNA segment of interest; and methods of effecting CRISPR-mediated gene editing in the eye. The present disclosure also provides compositions and methods for effecting base editing using base editors.[French]
La présente invention concerne : des systèmes rapporteurs pour l'édition génique médiée par CRISPR ; des ARNg, des ARN et des compositions pour les systèmes rapporteurs ; et des procédés de test de l'édition génique médiée par CRISPR. La présente invention concerne en outre des compositions et des procédés permettant d'éliminer un segment d'ADN d'intérêt ; et des procédés permettant d'effectuer une édition génique médiée par CRISPR dans l'œil. La présente invention fournit également des compositions et des procédés permettant d'effectuer une édition de bases à l'aide d'éditeurs de bases.