WO2023126672 - METHOD AND DEVICE FOR REMOVAL OF CIRCULATING CELL FREE DNA

National phase entry is expected:
Publication Number WO/2023/126672
Publication Date 06.07.2023
International Application No. PCT/IB2022/000665
International Filing Date 21.10.2022
Title **
[English] METHOD AND DEVICE FOR REMOVAL OF CIRCULATING CELL FREE DNA
[French] PROCÉDÉ ET DISPOSITIF D'ÉLIMINATION D'ADN ACELLULAIRE CIRCULANT
Applicants **
SANTERSUS AG
Inventors
SURKOV, Kirill
ASWANI, Andrew
Priority Data
63/294,024   27.12.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3183
EPO Filing, Examination, Granting17004
Japan Filing, Examination, Granting2493
South Korea Filing, Examination, Granting2756
USA Filing, Examination, Granting6390
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Total: 31,826

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Abstract[English] The invention provides apheresis devices and their use for substantial removal of all types of cfDNA for treatment of various diseases and during perfusion of an organ and/or anatomical cavity, to limit the negative effects of circulating cfDNA during organ transplantation and thus improve the quality and survival of transplanted organs, and reduce unfavorable transplantation outcomes such as transplant dysfunction, ischemia-reperfusion injury, graft rejection, and organ failure.[French] L'invention concerne des dispositifs d'aphérèse et leur utilisation pour l'élimination substantielle de tous les types d'ADNcf pour le traitement de diverses maladies et pendant la perfusion d'un organe et/ou d'une cavité anatomique, pour limiter les effets négatifs de l'ADNcf circulant pendant une transplantation d'organes et améliorer ainsi la qualité et la survie d'organes transplantés, et réduire des résultats de transplantation défavorables tels qu'un dysfonctionnement de greffe, une lésion d'ischémie-reperfusion, un rejet de greffe et une défaillance d'organe.