WO2022167867 - SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME
National phase entry:
Publication Number
WO/2022/167867
Publication Date
11.08.2022
International Application No.
PCT/IB2022/000060
International Filing Date
07.02.2022
Title **
[English]
SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME
[French]
MODULATEURS CYCLIQUES SUBSTITUÉS DE PROTÉINE PHOSPHATASE 2A (PP2A) ET LEURS PROCÉDÉS D'UTILISATION
Applicants **
RAPPTA THERAPEUTICS OY
Inventors
TRAINOR, George, L.
RABAL GRACIA, Maria, Obdulia
FOURMOIS, Laura
GHERBOVET, Olga
CACHOUX, Frederic
Priority Data
63/273,405
29.10.2021
US
63/191,405
21.05.2021
US
63/146,789
08.02.2021
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 12248 | |
| EPO | Filing, Examination, Granting | 380264 | |
| Japan | Filing, Examination, Granting | 6038 | |
| South Korea | Filing, Examination, Granting | 20330 | |
| USA | Filing, Examination, Granting | 67390 |
Total:
486,270
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present disclosure relates in part to chemical modulators of protein phosphatase 2A (PP2A). The compounds of the present disclosure are useful in treating, preventing, and/or ameliorating cancer, diabetes, autoimmune disease, solid organ transplant rejection, graft vs host disease, chronic obstructive pulmonary disease (COPD), non-alcoholic fatty liver disease, abdominal aortic aneurysm, chronic liver disease, heart failure, neurodegenerative disease, and cardiac hypertrophy.[French]
La présente divulgation concerne en partie des modulateurs chimiques de la protéine phosphatase 2A (PP2A). Les composés selon la présente divulgation sont utiles dans le traitement, la prévention et/ou le soulagement du cancer, du diabète, de maladies auto-immunes, du rejet de greffe d'organe solide, de la maladie du greffon contre l'hôte, de la broncho-pneumopathie chronique obstructive (BPCO), la stéatose hépatique non alcoolique, l'anévrisme aortique abdominal, une maladie hépatique chronique, une insuffisance cardiaque, une maladie neurodégénérative et une hypertrophie cardiaque.