WO2022090801 - PVRL2 AND/OR PVRIG AS BIOMARKERS FOR TREATMENT

National phase entry:
Publication Number WO/2022/090801
Publication Date 05.05.2022
International Application No. PCT/IB2021/000745
International Filing Date 26.10.2021
Title **
[English] PVRL2 AND/OR PVRIG AS BIOMARKERS FOR TREATMENT
[French] PVRL2 ET/OU PVRIG EN TANT QUE BIOMARQUEURS DE TRAITEMENT
Applicants **
COMPUGEN LTD.
Inventors
FRENKEL, Masha
OPHIR, Eran
KLIGER, Yossef
WEYL, Emmanuel
COJOCARU, Gad, S.
KFIR, Tal, Fridman
NOVIK, Amit
SABATH, Niv
ALTEBER, Zoya
Priority Data
63/257,026   18.10.2021   US
63/105,782   26.10.2020   US
63/213,629   22.06.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting10901
EPO Filing, Examination, Granting219567
Japan Filing, Examination, Granting5306
South Korea Filing, Examination, Granting12864
USA Filing, Examination, Granting52090
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Total: 300,728

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Abstract[English] The present invention provides biomarkers for use in determining populations for treatment with anti-PVRIG antibodies and such biomarkers include, for example PVRIG and/or PVRL2 expression.[French] La présente invention concerne des biomarqueurs destinés à être utilisés dans la détermination de populations pour un traitement avec des anticorps anti-PVRIG et ces biomarqueurs comprenant, par exemple, l'expression de PVRIG et/ou PVRL2.