WO2025224298 - INHIBITORS OF MALT1 AND METHODS OF THEIR USE
National phase entry is expected:
Publication Number
WO/2025/224298
Publication Date
30.10.2025
International Application No.
PCT/EP2025/061322
International Filing Date
25.04.2025
Title **
[English]
INHIBITORS OF MALT1 AND METHODS OF THEIR USE
[French]
INHIBITEURS DE MALT1 ET MÉTHODES POUR LEUR UTILISATION
Applicants **
JANSSEN PHARMACEUTICA NV
JOHNSON & JOHNSON (CHINA) INVESTMENT LTD.
Inventors
FONTAN GABAS, Lorena
HODKINSON, Brendan Paul
PHILIPPAR, Ulrike
SRINIVASAN, Srimathi Santhanam
MOWAT, Jeffrey Stuart
THURING, Johannes Wilhelmus J.
HULPIA, Fabian
LEPRI, Susan
PESCHIULLI, Aldo
VAN ROOSBROECK, Yves Emiel Maria
VELTER, Adriana-Ingrid
MUURONEN, Mikko Juhani Artturi
WROBLOWSKI, Berthold
Priority Data
PCT/CN2024/090170
26.04.2024
CN
PCT/CN2024/090178
26.04.2024
CN
PCT/CN2024/099801
18.06.2024
CN
PCT/CN2024/099802
18.06.2024
CN
63/662,020
20.06.2024
US
PCT/CN2024/101273
25.06.2024
CN
63/666,733
02.07.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2843 | |
| EPO | Filing, Examination, Granting | 11972 | |
| Japan | Filing, Examination, Granting | 2307 | |
| South Korea | Filing, Examination, Granting | 2576 | |
| USA | Filing, Examination, Granting | 4740 |

Total:
24,438
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Abstract[English]
Methods for treating a B-cell malignancy in a human subject are described. The methods involve determining the presence or absence of a B-cell activating mutation in a gene(s) obtained from the subject. Methods include treatment with the compound of formula (I).[French]
L'invention concerne des méthodes de traitement d'une malignité des lymphocytes B chez un sujet humain. Les méthodes consistent à déterminer la présence ou l'absence d'une mutation d'activation de lymphocytes B dans un ou plusieurs gènes obtenus à partir du sujet. Les méthodes comprennent le traitement avec le composé de formule (I).