WO2026119052 - METHOD FOR PROTECTING OR MAINTAINING CARDIOVASCULAR HEALTH, AND COMPOSITION
National phase entry is expected:
Publication Number
WO/2026/119052
Publication Date
11.06.2026
International Application No.
PCT/CN2025/138891
International Filing Date
01.12.2025
Title **
[English]
METHOD FOR PROTECTING OR MAINTAINING CARDIOVASCULAR HEALTH, AND COMPOSITION
[French]
PROCÉDÉ DE PROTECTION OU DE MAINTIEN DE LA SANTÉ CARDIOVASCULAIRE, ET COMPOSITION
[Chinese]
用于保护或维持心血管健康的方法及组合物
Applicants **
NANJING NUTRABUILDING BIO-TECH CO., LTD.
Inventors
ZHANG, Qianjing
WELLS, Shawn
LIAO, Kylin
Priority Data
PCT/CN2024/136604
04.12.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1836 | |
| EPO | Filing, Examination, Granting | 13621 | |
| Japan | Filing, Examination, Granting | 2279 | |
| South Korea | Filing, Examination, Granting | 2403 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
24,879
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Abstract[English]
Provided is a method for protecting or maintaining cardiovascular health, comprising administering to a subject a composition containing dehydrozingerone or a salt, acid, ester or derivative thereof. The composition prevents atherosclerosis, regulates the function of vascular endothelial cells, and modulates vasomotor activity and permeability by inhibiting the expression of vascular cell adhesion molecule-1 (VCAM-1) or intercellular adhesion molecule-1 (ICAM-1), or by increasing the content of nitric oxide, thereby significantly enhancing cardiovascular health. Also provided are a composition containing dehydrozingerone or a salt, acid, ester or derivative thereof, and a use of the composition in preparation of nutritional products, dietary supplements, foods, beverages or animal feeds for protecting or maintaining cardiovascular health.[French]
L'invention concerne un procédé de protection ou de maintien de la santé cardiovasculaire, consistant à administrer à un sujet une composition contenant de la déhydrozingérone ou un sel, un acide, un ester ou un dérivé de celle-ci. La composition empêche l'athérosclérose, régule la fonction de cellules endothéliales vasculaires et module l'activité et la perméabilité vasomotrices par inhibition de l'expression de la molécule d'adhérence cellulaire vasculaire-1 (VCAM-1) ou de la molécule d'adhérence intercellulaire-1 (ICAM-1), ou par augmentation de la teneur en oxyde nitrique, ce qui permet d'améliorer de manière significative la santé cardiovasculaire. L'invention concerne également une composition contenant de la déhydrozingérone ou un sel, un acide, un ester ou un dérivé de celle-ci, et une utilisation de la composition dans la préparation de produits nutritionnels, de compléments alimentaires, d'aliments, de boissons ou d'aliments pour animaux pour protéger ou maintenir la santé cardiovasculaire.[Chinese]
一种保护或维持心血管健康的方法，包括向受试者施用含脱氢姜酮或其盐、酸、酯或衍生物的组合物。该组合物通过抑制血管细胞粘附分子-1 (VCAM-1)或细胞间粘附分子-1 (ICAM-1)的表达，或增加一氧化氮的含量，进而预防动脉粥样硬化，调节血管内皮细胞的功能，调节血管舒缩和通透性，从而显著改善心血管健康。还涉及一种含脱氢姜酮或其盐、酸、酯或衍生物的组合物，以及该组合物在制备用于保护或维持心血管健康的营养品、膳食补充剂、食品、饮料或动物饲料的用途。