WO2026114345 - PHOSPHATE OF PYRROLOPYRIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR
National phase entry is expected:
Publication Number
WO/2026/114345
Publication Date
04.06.2026
International Application No.
PCT/CN2025/138341
International Filing Date
28.11.2025
Title **
[English]
PHOSPHATE OF PYRROLOPYRIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR
[French]
PHOSPHATE DE DÉRIVÉ DE PYRROLOPYRIDINE ET SON PROCÉDÉ DE PRÉPARATION
[Chinese]
吡咯并吡啶类衍生物的磷酸盐及其制备方法
Applicants **
ALICORN PHARMACEUTICAL CO., LTD
JIANGSU ALICORN PHARMACEUTICAL TECHNOLOGY CO., LTD.
Inventors
LU, Pingbo
ZHU, Hui
YANG, Jiale
GAO, Chao
XU, Kui
ZHOU, Ying
ZHU, Chao
Priority Data
202411744873.3
29.11.2024
CN
Application details
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International Searching Authority |
CNIPA
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| 译文 |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1836 | |
| EPO | Filing, Examination, Granting | 13621 | |
| Japan | Filing, Examination, Granting | 2279 | |
| South Korea | Filing, Examination, Granting | 2403 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
24,879
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Abstract[English]
Provided are phosphate of (S)-1-((2-(difluoromethyl)-6-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-3-yl)oxy)-2,4-dimethylpentan-2-amine, various crystal forms thereof, a pharmaceutical composition thereof, and the use thereof in the treatment of AAK1-related diseases.[French]
L'invention concerne un phosphate de (S)-1-((2-(difluorométhyl)-6-(5-fluoro-1H-pyrrolo [2,3-b] pyridin-3-yl)pyridin-3-yl)oxy)-2,4-diméthylpentan-2-amine, diverses formes cristallines de celui-ci, une composition pharmaceutique de celui-ci, et son utilisation dans le traitement de maladies associées à AAK1.[Chinese]
(S)-1- ((2-(二氟甲基)-6- (5-氟-1H-吡咯并[2,3-b]吡啶-3-基)吡啶-3-基)氧基)-2,4-二甲基戊烷-2-胺的磷酸盐、其多种晶型、药物组合物及其治疗AAK1相关疾病的应用。