WO2026021557 - PHARMACEUTICAL COMPOSITION OF BENZINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

National phase entry is expected:
Publication Number WO/2026/021557
Publication Date 29.01.2026
International Application No. PCT/CN2025/110492
International Filing Date 25.07.2025
Title **
[English] PHARMACEUTICAL COMPOSITION OF BENZINDOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF
[French] COMPOSITION PHARMACEUTIQUE D'UN DÉRIVÉ DE BENZINDOLE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese] 苯并吲哚衍生物的药物组合物、制备方法及用途
Applicants **
SHANGHAI HELIOSON PHARMACEUTICAL CO.
Inventors
ZHAO, Liwen
ZHANG, Kefeng
XU, Zheng
WANG, Dihuang
Priority Data
202411015044.1   26.07.2024   CN
202411315301.3   20.09.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1661
EPO Filing, Examination, Granting11551
Japan Filing, Examination, Granting2030
South Korea Filing, Examination, Granting1900
USA Filing, Examination, Granting4740
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Abstract[English] The present application relates to the technical field of pharmaceutical formulations and particularly to a pharmaceutical composition of a benzindole derivative, a preparation method therefor, and use thereof. The pharmaceutical composition comprises a compound represented by formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient, and one or more pharmaceutically acceptable excipients. The active ingredient in the pharmaceutical composition demonstrates good dissolution and excellent absorption in an organism, and the pharmaceutical composition remains stable even during long-term storage.[French] La présente invention concerne le domaine technique des formulations pharmaceutiques et en particulier une composition pharmaceutique d'un dérivé de benzindole, son procédé de préparation et son utilisation. La composition pharmaceutique comprend un composé représenté par la formule (I) ou un sel pharmaceutiquement acceptable de celui-ci en tant que principe actif, et un ou plusieurs excipients pharmaceutiquement acceptables. Le principe actif dans la composition pharmaceutique présente une bonne dissolution et une excellente absorption dans un organisme, et la composition pharmaceutique reste stable même pendant un stockage à long terme.[Chinese] 本申请涉及药物制剂技术领域,具体涉及一种苯并吲哚衍生物的药物组合物、制备方法及用途;所示药物组合物包括活性成分式(I)所示化合物或其药学上可接受的盐以及一种或多种药学上可接受的辅料;所述药物组合物中活性成分溶出性好,在生物体内的吸收性优异,药物组合物即使长期保存也稳定。