WO2026021539 - BICYCLIC IL-17A/F INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2026/021539
Publication Date
29.01.2026
International Application No.
PCT/CN2025/110368
International Filing Date
24.07.2025
Title **
[English]
BICYCLIC IL-17A/F INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
[French]
INHIBITEUR D'IL-17A/F BICYCLIQUE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese]
双环IL-17A/F抑制剂及其制备方法与应用
Applicants **
SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD
Inventors
LAI, Yingjie
XIONG, Jinfeng
DUAN, Zhenfang
LIU, Hanbin
DENG, Shenglu
XIAO, Wanlong
ZHANG, Cairong
XIAO, Ying
ZHOU, Yuwei
Priority Data
202411003084.4
24.07.2024
CN
202411000668.6
24.07.2024
CN
202411269289.7
10.09.2024
CN
202411517559.1
28.10.2024
CN
202411836915.6
11.12.2024
CN
202510557753.0
28.04.2025
CN
202510977887.8
15.07.2025
CN
202511019233.0
22.07.2025
CN
Application details
| Total Number of Claims/PCT | * |
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International Searching Authority |
CNIPA
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2137 | |
| EPO | Filing, Examination, Granting | 11730 | |
| Japan | Filing, Examination, Granting | 2122 | |
| South Korea | Filing, Examination, Granting | 2295 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
23,024
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Abstract[English]
The present application relates to the technical field of chemical drugs, provides a bicyclic IL-17A/F inhibitor compound, and a preparation method therefor and a use thereof, and specifically relates to a compound represented by general formula (I), or a racemate thereof, or an isomer thereof, or a pharmaceutically acceptable salt thereof, and a use thereof as an IL-17A/F inhibitor for treating diseases such as psoriasis and arthritis.[French]
La présente invention concerne le domaine technique des médicaments chimiques, fournit un composé inhibiteur d'IL-17A/F bicyclique, son procédé de préparation et son utilisation, et concerne spécifiquement un composé représenté par la formule générale (I), ou un racémate de celui-ci, ou un isomère de celui-ci, ou un sel pharmaceutiquement acceptable de celui-ci, et une utilisation de celui-ci en tant qu'inhibiteur d'IL-17A/F pour le traitement de maladies telles que le psoriasis et l'arthrite.[Chinese]
本申请属于化学药物技术领域，提供一种双环IL-17A/F抑制剂化合物及其制备方法与应用，具体涉及通式(I)所示的化合物，或其消旋体、或其异构体、或其可药用的盐，作为IL-17A/F抑制剂，用于治疗银屑病、关节炎等疾病。