WO2025237418 - SALT AND CRYSTAL FORM OF CDK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/237418
Publication Date 20.11.2025
International Application No. PCT/CN2025/095535
International Filing Date 16.05.2025
Title **
[English] SALT AND CRYSTAL FORM OF CDK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF
[French] SEL ET FORME CRISTALLINE D'UN INHIBITEUR DE CDK2, LEUR PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION
[Chinese] 一种CDK2抑制剂的盐、晶型及其制备方法和应用
Applicants **
SHANDONG LUYE PHARMACEUTICAL CO., LTD.
Inventors
LIU, Huifeng
LIAO, Wensheng
SUN, Runzhi
QU, Hao
WU, Yanhua
WANG, Guanghui
Priority Data
202410614141.6   17.05.2024   CN
202410971878.3   19.07.2024   CN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1934
EPO Filing, Examination, Granting12537
Japan Filing, Examination, Granting2186
South Korea Filing, Examination, Granting2237
USA Filing, Examination, Granting10140
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Total: 29,034
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Abstract[English] The present invention relates to a salt and a crystal form of a CDK2 inhibitor, and a preparation method therefor and the use thereof. Specifically, provided are a salt and a crystal form of a compound of formula I, a preparation method therefor, and the use thereof in the preparation of a drug for preventing or treating CDK2-mediated related diseases.[French] La présente invention concerne un sel et une forme cristalline d'un inhibiteur de CDK2, leur procédé de préparation et leur utilisation. Plus particulièrement, l'invention concerne un sel et une forme cristalline d'un composé de formule I, leur procédé de préparation et leur utilisation dans la préparation d'un médicament pour la prévention ou le traitement de maladies associées à une médiation par CDK2.[Chinese] 本发明涉及一种CDK2抑制剂的盐、晶型及其制备方法和应用。具体而言,提供了式I化合物的盐、晶型、制备方法,以及在制备预防或治疗CDK2介导的相关疾病的药物中的应用。