WO2025228411 - MONOAMINE TRANSMITTER REUPTAKE INHIBITOR COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF

National phase entry is expected:
Publication Number WO/2025/228411
Publication Date 06.11.2025
International Application No. PCT/CN2025/092337
International Filing Date 30.04.2025
Title **
[English] MONOAMINE TRANSMITTER REUPTAKE INHIBITOR COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
[French] COMPOSÉ INHIBITEUR DE RECAPTURE DE MONOAMINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
[Chinese] 一类单胺递质再摄取抑制剂化合物及其制备方法和应用
Applicants **
SHANDONG QUANZHONG BIOMEDICAL TECHNOLOGY CO., LTD.
Inventors
TIAN, Jingwei
YE, Liang
ZHANG, Jianzhao
LIAO, Wensheng
DAI, Yusen
XU, Hengwei
LIU, Zongliang
LEI, Hui
WANG, Wenyan
YANG, Huijie
Priority Data
202410542159.X   30.04.2024   CN
202411138885.1   19.08.2024   CN
202510117370.1   24.01.2025   CN
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2208
EPO Filing, Examination, Granting13797
Japan Filing, Examination, Granting2216
South Korea Filing, Examination, Granting2336
USA Filing, Examination, Granting4740
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Total: 25,297
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Abstract[English] The present invention provides a monoamine transmitter reuptake inhibitor and a preparation method therefor and a pharmaceutical composition thereof, and further relates to a use of the compound or the pharmaceutical composition in preparation of a drug for preventing or treating dopamine (DA), norepinephrine (NE), 5-hydroxytryptamine (5-HT), and/or sigma-1 receptor-mediated related diseases.[French] La présente invention concerne un inhibiteur de recapture de monoamine, son procédé de préparation et une composition pharmaceutique de celui-ci, et concerne en outre une utilisation du composé ou de la composition pharmaceutique dans la préparation d'un médicament pour la prévention ou le traitement de la dopamine (DA), de la norépinéphrine (NE), de la 5-hydroxytryptamine (5-HT) et/ou de maladies associées à médiation par le récepteur sigma-1.[Chinese] 本发明提供了一类单胺递质再摄取抑制剂及其制备方法和药物组合物。还涉及含有所述化合物或药物组合物在制备预防或治疗多巴胺DA、去甲肾上腺素NE、5-羟色胺5-HT、和/或sigma-1受体介导的相关疾病的药物中的应用。