WO2025218615 - HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF IN MEDICINE

National phase entry is expected:
Publication Number WO/2025/218615
Publication Date 23.10.2025
International Application No. PCT/CN2025/088697
International Filing Date 14.04.2025
Title **
[English] HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF IN MEDICINE
[French] COMPOSÉ AMIDE HÉTÉROCYCLIQUE ET SON UTILISATION EN MÉDECINE
[Chinese] 一种杂环酰胺类化合物及其在医药上的应用
Applicants **
HANGZHOU BAICREAT PHARMA-TECH CO., LTD.
Inventors
ZHANG, Fengmin
GU, Dongyan
Priority Data
202410450896.7   15.04.2024   CN
202411097520.9   12.08.2024   CN
202411331686.2   24.09.2024   CN
202510066265.X   16.01.2025   CN
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2838
EPO Filing, Examination, Granting23183
Japan Filing, Examination, Granting2770
South Korea Filing, Examination, Granting3555
USA Filing, Examination, Granting7740
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Total: 40,086
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Abstract[English] The present invention relates to the technical field of medicine, and in particular to a Polθ inhibitor, a preparation method therefor and a use thereof in medicine. The present invention provides a Polθ inhibitor represented by formula (Ia) or (Ib), a composition comprising same and a use thereof, wherein the compound can be used for treating or preventing Polθ-mediated diseases or disorders and related diseases or disorders.[French] La présente invention se rapporte au domaine technique de la médecine et concerne en particulier un inhibiteur de Polθ, son procédé de préparation et son utilisation en médecine. La présente invention concerne un inhibiteur de Polθ représenté par la formule (Ia) ou (Ib), une composition le comprenant et une utilisation de celui-ci, le composé pouvant être utilisé pour traiter ou prévenir des maladies ou troubles médiés par Polθ et des maladies ou troubles associés.[Chinese] 本发明涉及医药技术领域,具体涉及Polθ抑制剂、其制备方法及其在医药上的应用。本发明提供了一种式(Ia)或(Ib)所述Polθ抑制剂及其组合物和用途,所述化合物可以用于治疗或预防Polθ介导的疾病或病症及相关疾病或病症。