WO2025190405 - NITROGEN-CONTAINING WRN INHIBITOR COMPOUND AND USE THEREOF
National phase entry is expected:
Publication Number
WO/2025/190405
Publication Date
18.09.2025
International Application No.
PCT/CN2025/082699
International Filing Date
14.03.2025
Title **
[English]
NITROGEN-CONTAINING WRN INHIBITOR COMPOUND AND USE THEREOF
[French]
COMPOSÉ INHIBITEUR DE WRN CONTENANT DE L'AZOTE ET SON UTILISATION
[Chinese]
含氮WRN抑制剂化合物及其应用
Applicants **
NANJING ZAIMING PHARMACEUTICAL CO., LTD.
Inventors
WANG, Juan
YANG, Yang
ZHOU, Muxing
WANG, Weikun
YU, Jian
LI, Zhengtao
TANG, Renhong
Priority Data
202410302258.0
15.03.2024
CN
202410522277.4
28.04.2024
CN
202410791143.2
19.06.2024
CN
202411083298.7
08.08.2024
CN
202411383227.9
30.09.2024
CN
202510071096.9
16.01.2025
CN
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
CNIPA
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| 译文 |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2197 | |
| EPO | Filing, Examination, Granting | 13108 | |
| Japan | Filing, Examination, Granting | 2216 | |
| South Korea | Filing, Examination, Granting | 2434 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
24,695
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Abstract[English]
The present disclosure provides a nitrogen-containing WRN inhibitor compound represented by formula (I) or a pharmaceutically acceptable salt or a stereoisomer thereof, a pharmaceutical composition comprising same, and a use thereof as a WRN inhibitor in preventing or treating related diseases.[French]
La présente invention concerne un composé inhibiteur de WRN contenant de l'azote représenté par la formule (I) ou un sel pharmaceutiquement acceptable ou un stéréoisomère de celui-ci, une composition pharmaceutique le comprenant, et son utilisation en tant qu'inhibiteur de WRN dans la prévention ou le traitement de maladies associées.[Chinese]
本公开提供了一种式(I)所示的含氮WRN抑制剂化合物或其药学可接受的盐或其立体异构体，含有它们的药物组合物以及其作为WRN抑制剂在预防或治疗相关疾病中的应用。