WO2025185741 - GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENES

National phase entry is expected:
Publication Number WO/2025/185741
Publication Date 11.09.2025
International Application No. PCT/CN2025/081345
International Filing Date 07.03.2025
Title **
[English] GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC GENES
[French] ANIMAL NON HUMAIN GÉNÉTIQUEMENT MODIFIÉ EXPRIMANT DES GÈNES HUMAINS OU CHIMÉRIQUES
Applicants **
BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD.
Inventors
WANG, Linlin
LV, Ruili
FU, Shaozu
ZHANG, Meiqi
GUO, Jing
Priority Data
202410266881.5   08.03.2024   CN
202410742436.1   07.06.2024   CN
202411131695.7   16.08.2024   CN
202411426464.9   12.10.2024   CN
202510094101.8   21.01.2025   CN
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译文

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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting6102
EPO Filing, Examination, Granting133883
Japan Filing, Examination, Granting4943
South Korea Filing, Examination, Granting9701
USA Filing, Examination, Granting40640
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Total: 195,269
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Abstract[English] Provided are genetically modified non-human animals that express human or chimeric (e.g., humanized) IL12RB1, IL12RB2, and/ or IL23R, and methods of use thereof.[French] L'invention concerne des animaux non humains génétiquement modifiés exprimant IL12RB1, IL12RB2, et/ou IL23R humains ou chimériques (par exemple, humanisés), et leurs procédés d'utilisation.