WO2025226842 - EXPRESSION CONTROL BY DRG-EXPRESSED MIRNAS

National phase entry is expected:
Publication Number WO/2025/226842
Publication Date 30.10.2025
International Application No. PCT/US2025/026016
International Filing Date 23.04.2025
Title **
[English] EXPRESSION CONTROL BY DRG-EXPRESSED MIRNAS
[French] CONTRÔLE D'EXPRESSION PAR DES ARNMI EXPRIMÉS PAR DRG
Applicants **
KATE THERAPEUTICS, INC.
Inventors
SESHADRI, Saurav
TABEBORDBAR, Mohammadsharif
TABEBORDBAR, Shayan
Priority Data
63/638,126   24.04.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2191
EPO Filing, Examination, Granting10814
Japan Filing, Examination, Granting2327
South Korea Filing, Examination, Granting2360
USA Filing, Examination, Granting4740
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Total: 22,432
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Abstract[English] , vectors such as viral vectors) that express a transgene and at least one binding site of at least one microRNA (miR) selected from miR-338-3p, miR-138-5p, and miR-9-5p, which selectively inhibit expression of the transgene in the dorsal root ganglia (DRG).[French] , des vecteurs tels que des vecteurs viraux) qui expriment un transgène et au moins un site de liaison d'au moins un microARN (miR) choisi parmi miR-338-3p, miR-138-5p et miR-9-5p, qui inhibent sélectivement l'expression du transgène dans les ganglions de la racine dorsale (DRG).

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