WO2025160448 - B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF
National phase entry is expected:
Publication Number
WO/2025/160448
Publication Date
31.07.2025
International Application No.
PCT/US2025/013017
International Filing Date
24.01.2025
Title **
[English]
B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF
[French]
PEPTIDES CIBLANT B7-H3 ET CONSTRUCTIONS ASSOCIÉES
Applicants **
MARIANA ONCOLOGY INC.
Inventors
HUANG, Chunhui
METCALF III, Chester A.
UPADHYAYA, Punit
MA, Zhong
RICARDO, Alonso
WU, Lihua
SINGH, Alok
WAN, Murray
BIANCHI, Elisabetta
CONSTANTINI, Willy
NIZI, Emanuela
Priority Data
63/625,649
26.01.2024
US
63/625,696
26.01.2024
US
63/728,093
04.12.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 9664 | |
| EPO | Filing, Examination, Granting | 67340 | |
| Japan | Filing, Examination, Granting | 3886 | |
| South Korea | Filing, Examination, Granting | 5511 | |
| USA | Filing, Examination, Granting | 21340 |
Total:
107,741
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Abstract[English]
The present disclosure relates to targeting moieties such as peptides that can bind to B7-H3. The disclosure also provides targeting constructs, which may include a targeting moiety attached, via an optional linker, to a chelating agent for association of a cargo. Methods of making the constructs and formulations thereof are also provided. Methods of using the constructs and/or formulations thereof to treat subjects, for example, to treat or prevent cancer, are also described.[French]
La présente divulgation concerne des fractions de ciblage telles que des peptides qui peuvent se lier à B7-H3. L'invention concerne également des constructions de ciblage, qui peuvent comprendre une fraction de ciblage fixée, par l'intermédiaire d'un lieur facultatif, à un agent chélatant pour l'association d'une molécule cargo. L'invention concerne également des procédés de fabrication des constructions et des formulations associées. L'invention concerne également des procédés d'utilisation des constructions et/ou des formulations associées pour traiter des sujets, par exemple, pour traiter ou prévenir le cancer.