WO2025010224 - INTRANASAL DELIVERY

National phase entry:
Publication Number WO/2025/010224
Publication Date 09.01.2025
International Application No. PCT/US2024/036371
International Filing Date 01.07.2024
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[English] INTRANASAL DELIVERY
[French] ADMINISTRATION INTRANASALE
Applicants **
VIRPAX PHARMACEUTICALS INC.
Inventors
UCHEGBU, Ijeoma
SCHATZLEIN, Andreas
MACK, Anthony
MATHIAS, Sheila
Priority Data
63/524,764   03.07.2023   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3242
EPO Filing, Examination, Granting26959
Japan Filing, Examination, Granting3017
South Korea Filing, Examination, Granting3879
USA Filing, Examination, Granting10510
MasterCard Visa
Total: 47,607

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to formulations, devices and delivery of leucine-5-enkephalin (LENK) formulated with N-palmitoyl-N-acetyl-N-monomethyl-N,N-dimethyl-N,N,N-trimethyl-6-O-glycolchitosan (GCPQor Molecular Envelope Technology - MET). In particular, the present invention relates to delivering leucine-5-enkephalin encapsulated in GCPQ. intranasally via a drug or medicine dispersion and delivery system. The dispersion methods employ curved surfaces to impart rotational motions to one or more fluid flows from a pressurized container to create turbulence and improve mixing of medicament with fluid.[French] La présente invention concerne des formulations, des dispositifs et l'administration de leucine-5-enképhaline (LENK) formulée avec du N-palmitoyl-N-acétyl-N-monométhyl-N,N-diméthyl-N,N,N-triméthyl-6-O-glycolchitosane (GCPQ ou Technologie d'enveloppe moléculaire - MET). En particulier, la présente invention concerne l'administration de leucine-5-enképhaline encapsulée dans du GCPQ par voie intranasale par l'intermédiaire d'un médicament ou d'une dispersion de médicament et d'un système d'administration. Les procédés de dispersion utilisent des surfaces incurvées pour conférer des mouvements de rotation à un ou à plusieurs écoulements de fluide depuis un récipient sous pression pour créer une turbulence et améliorer le mélange d'un médicament avec un fluide.

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