WO2023240212 - GENETICALLY ENGINEERED CELLS HAVING ANTI-CD133 / ANTI-EGFR CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOF

National phase entry is expected:
Publication Number WO/2023/240212
Publication Date 14.12.2023
International Application No. PCT/US2023/068159
International Filing Date 08.06.2023
Title **
[English] GENETICALLY ENGINEERED CELLS HAVING ANTI-CD133 / ANTI-EGFR CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOF
[French] CELLULES GÉNÉTIQUEMENT MODIFIÉES AYANT DES RÉCEPTEURS ANTIGÉNIQUES CHIMÉRIQUES ANTI-CD133/ANTI-CD22, ET LEURS UTILISATIONS
Applicants **
CENTURY THERAPEUTICS, INC.
Inventors
NASO, Michael, Francis
CARTON, Jill, Marinari
VORA, Parvez
BORGES, Luis
DOWER, Christopher
BLOEMBERG, Darin
Priority Data
63/350,380   08.06.2022   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4348
EPO Filing, Examination, Granting48560
Japan Filing, Examination, Granting3728
South Korea Filing, Examination, Granting5092
USA Filing, Examination, Granting20790
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Total: 82,518

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] Provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing mono- and/or bi-specific chimeric antigen receptors (CAR) with anti-CD133 and anti-EGFR antigen binding domains, and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.[French] L'invention concerne des cellules souches pluripotentes induites (iPSC) génétiquement modifiées et des cellules dérivées de celles-ci exprimant des récepteurs antigéniques chimériques (CAR) mono-et/ou bi-spécifiques avec des domaines de liaison à l'antigène anti-CD133 et anti-EGFR, et leurs méthodes d'utilisation. L'invention concerne également des compositions, des polypeptides, des vecteurs et des méthodes de fabrication.

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