WO2023101993 - SEGMENTED NUCLEIC ACIDS

National phase entry:
Publication Number WO/2023/101993
Publication Date 08.06.2023
International Application No. PCT/US2022/051309
International Filing Date 30.11.2022
Title **
[English] SEGMENTED NUCLEIC ACIDS
[French] ACIDES NUCLÉIQUES SEGMENTÉS
Applicants **
ZHONG, Minghong
Inventors
ZHONG, Minghong
Priority Data
17/839,539   14.06.2022   US
63/284,025   30.11.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2735
EPO Filing, Examination, Granting13390
Japan Filing, Examination, Granting2546
South Korea Filing, Examination, Granting2789
USA Filing, Examination, Granting7310
MasterCard Visa
Total: 28,770

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] Provided herein are processes and methods for preparation of segmented nucleic acids and segmented nucleic acid conjugates comprising at least two non-nucleotide linkers, and their RNP complexes with RNA guided gene editing proteins including CRISPR Cas proteins and ADAR enzymes. Also disclosed are the uses of the compositions comprising segmented nucleic acids or segmented nucleic acid conjugates as medicinal agents for treatment of diseases.[French] La présente divulgation concerne des processus et des procédés de préparation d'acides nucléiques segmentés et de conjugués d'acides nucléiques segmentés comprenant au moins deux lieurs non nucléotidiques, et leurs complexes RNP avec des protéines d'édition génique guidée par ARN comprenant des protéines CRISPR-Cas et des enzymes ADAR. La divulgation concerne également les utilisations des compositions comprenant des acides nucléiques segmentés ou des conjugués d'acides nucléiques segmentés en tant qu'agents médicamenteux pour le traitement de maladies.

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