WO2023014853 - HPV VACCINE

National phase entry:
Publication Number WO/2023/014853
Publication Date 09.02.2023
International Application No. PCT/US2022/039371
International Filing Date 04.08.2022
Title **
[English] HPV VACCINE
[French] VACCIN ANTI-VPH
Applicants **
MERCK SHARP & DOHME LLC
BETT, Andrew
BILELLO, John, P.
CEJAS, Pedro, J.
ESPESETH, Amy, S.
FU, Tong-Ming
STRABLE, Erica, L.
BARR, Colleen, M.
ZIMMERMANN, Sara
Inventors
BETT, Andrew
BILELLO, John, P.
CEJAS, Pedro, J.
ESPESETH, Amy, S.
FU, Tong-Ming
STRABLE, Erica, L.
BARR, Colleen, M.
ZIMMERMANN, Sara
Priority Data
63/230,426   06.08.2021   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting4520
EPO Filing, Examination, Granting77706
Japan Filing, Examination, Granting4531
South Korea Filing, Examination, Granting6393
USA Filing, Examination, Granting22140
MasterCard Visa
Total: 115,290

The term for entry into the National Phase has expired. This quotation is for informational purposes only

Abstract[English] The present disclosure provides, among other things, a single-dose vaccine composition that includes a chitosan adjuvant and HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82, where the single-dose vaccine composition provides enhanced or comparable HPV vaccine response in comparison to a similar multiple-dose vaccine formulated without such chitosan adjuvant.[French] La présente divulgation concerne, entre autres, une composition de vaccin à dose unique qui comprend un adjuvant de chitosane et des particules de type virus VPH (PPV) d'au moins un type de papillomavirus humain (VPH) choisi dans le groupe constitué par les types de VPH : 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73 et 82, la composition de vaccin à dose unique fournissant une réponse de vaccin VPH améliorée ou comparable par rapport à un vaccin à dose multiple similaire formulé sans un tel adjuvant de chitosane.

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