WO2025105973 - PROCESS FOR INCREASING THE BIOAVAILABILITY OF BIOACTIVE COMPOUNDS IN BEE POLLEN
National phase entry is expected:
Publication Number
WO/2025/105973
Publication Date
22.05.2025
International Application No.
PCT/RO2024/000025
International Filing Date
15.11.2024
Title **
[English]
PROCESS FOR INCREASING THE BIOAVAILABILITY OF BIOACTIVE COMPOUNDS IN BEE POLLEN
[French]
PROCÉDÉ POUR AUGMENTER LA BIODISPONIBILITÉ DE COMPOSÉS BIOACTIFS DANS LE POLLEN D'ABEILLES
Applicants **
VIO NUTRI LAB SRL
Inventors
TRYVYZAS, Nikos
TRITEAN, Naomi
CONSTANTINESCU-ARUXANDEI, Diana
OANCEA, Florin
DIMITRIU, Luminiţa
Priority Data
a202300698
15.11.2023
RO
Application details
| Total Number of Claims/PCT | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Pages of Specification | * |
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| Number of Office Actions | * |
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International Searching Authority |
Rospatent
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1955 | |
| EPO | Filing, Examination, Granting | 11611 | |
| Japan | Filing, Examination, Granting | 1734 | |
| South Korea | Filing, Examination, Granting | 1201 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
21,241
The term for entry into the National Phase has expired. This quotation is for informational purposes only
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Abstract[English]
The present invention relates to a process for increasing the bioavailability and efficacy of bioactive compounds in bee-collected pollen, primarily polyphenols and biosilica, with the aim of improving the quality of nutritional supplements, medical devices, and/or cosmetic products based on pollen. The process is characterized by comprising the following steps: semi-solid fermentation of bee-collected pollen, homogenized together with polyfloral honey at 9.5 grams of pollen, at room temperature, for 2 days; mixing 30 grams of semi-solid fermented pollen with 200 ml of distilled water and ultrasonication for 5 minutes at 750 W and a frequency of 30 kHz; adding to the 30 grams of semi-solid fermented pollen, homogenized in 200 ml of water, 8 grams of wheat bran and 4 grams of chaff containing at least 10A8 cfu/g lactobacilli, and fermenting for 3 days at 30 degrees; colloidal grinding of the fermented pollen, bran, and chaff, together with the fermentation medium for 1 minute, ultrasonication for 20 minutes at 750W and a frequency of 30 kHz, followed by cooling the mixture at 4°C for 2 hours and drying by lyophilization.[French]
La présente invention concerne un procédé pour augmenter la biodisponibilité et l'efficacité de composés bioactifs dans du pollen collecté par les abeilles, principalement des polyphénols et de la biosilice, dans le but d'améliorer la qualité de compléments nutritionnels, de dispositifs médicaux et/ou de produits cosmétiques à base de pollen. Le procédé est caractérisé en ce qu'il comprend les étapes suivantes : fermentation à l'état semi-solide du pollen collecté par les abeilles, homogénéisé avec du miel polyfloral à raison de 9,5 grammes de pollen, à température ambiante, pendant 2 jours; mélange de 30 grammes de pollen fermenté semi-solide avec 200 ml d'eau distillée et ultrasonication pendant 5 minutes à 750 W et à une fréquence de 30 kHz; ajout aux 30 grammes de pollen fermenté semi-solide, homogénéisés dans 200 ml d'eau, de 8 grammes de son de blé et 4 grammes de bale contenant au moins 10A8 cfu/g de lactobacilles, et fermentation pendant 3 jours à 30 degrés; broyage colloïdal du pollen fermenté, du son et de la bale, conjointement avec le milieu de fermentation pendant 1 minute, ultrasonication pendant 20 minutes à 750 W et à une fréquence de 30 kHz, puis refroidissement du mélange à 4°C pendant 2 heures et séchage par lyophilisation.