WO2026094064 - PROCESS FOR THE SYNTHESIS OF INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF GALNAC (L96) CONJUGATED OLIGONUCLEOTIDES
National phase entry is expected:
Publication Number
WO/2026/094064
Publication Date
07.05.2026
International Application No.
PCT/IN2025/051691
International Filing Date
22.10.2025
Title **
[English]
PROCESS FOR THE SYNTHESIS OF INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF GALNAC (L96) CONJUGATED OLIGONUCLEOTIDES
[French]
PROCÉDÉ POUR LA SYNTHÈSE DE COMPOSÉS INTERMÉDIAIRES UTILES POUR LA PRÉPARATION D'OLIGONUCLÉOTIDES CONJUGUÉS DE GALNAC (L96)
Applicants **
NATCO PHARMA LIMITED
Inventors
KAPARAPU, Phaneendra
AWACHAT, Ragini Raghuvir
SABALE, Pramod Madhavrao
MUDDASANI, Pulla Reddy
NANNAPANENI, Venkaiah Chowdary
Priority Data
202441083201
30.10.2024
IN
Application details
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International Searching Authority |
IP India
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 1954 | |
| EPO | Filing, Examination, Granting | 11600 | |
| Japan | Filing, Examination, Granting | 2025 | |
| South Korea | Filing, Examination, Granting | 1783 | |
| USA | Filing, Examination, Granting | 4740 |
Total:
22,102
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Abstract[English]
The present invention relates to a simple and cost-effective improved process for the preparation of GalNAc (L96) conjugated oligonucleotides. The present invention relates to a simple and cost-effective improved process for the preparation of intermediate of GalNAc (L96) conjugated oligonucleotides compound of Formulae-(I) & (Ia). Formula-(I) Formula-(Ia)[French]
La présente invention concerne un procédé amélioré, simple et économique pour la préparation d'oligonucléotides conjugués GalNAc (L96). La présente invention concerne un procédé amélioré, simple et économique pour la préparation d'un intermédiaire de composé d'oligonucléotides conjugués GalNAc (L96) de formules-(I) et (Ia). Formule-(I), Formule-(Ia)