WO2026058288 - PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF RADIATION INDUCED TOXICITY

National phase entry is expected:
Publication Number WO/2026/058288
Publication Date 19.03.2026
International Application No. PCT/IN2025/051488
International Filing Date 12.09.2025
Title **
[English] PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF RADIATION INDUCED TOXICITY
[French] COMPOSITION PHARMACEUTIQUE POUR LE TRAITEMENT DE LA TOXICITÉ INDUITE PAR UN RAYONNEMENT
Applicants **
ZYDUS LIFESCIENCES LIMITED
Inventors
JAIN, Mukul
JOHARAPURKAR, Amit
PATEL, Vishal
KOTHARI, Jay
KANNAN, Muthaiyyan Essakimuthu
LADDHA, Ritu
UKAWALA, Mukesh
SAHU, Sunil
Priority Data
202421069288   13.09.2024   IN
202421073122   27.09.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3252
EPO Filing, Examination, Granting25513
Japan Filing, Examination, Granting2918
South Korea Filing, Examination, Granting3728
USA Filing, Examination, Granting12140
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Total: 47,551
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Abstract[English] The present invention relates to parenteral pharmaceutical compositions of suitable Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor, particularly to Desidustat or suitable pharmaceutically acceptable salts thereof. The invention also relates to processes for preparing such compositions. The present invention also relates to the development of therapeutic compound for the treatment of radiation induced toxicity. Specifically, present invention relates to use of Desidustat or its pharmaceutically acceptable salt or oral and parenteral pharmaceutical composition thereof for the treatment of radiation induced toxicity.[French] La présente invention concerne des compositions pharmaceutiques parentérales d'inhibiteur de la prolyl hydroxylase du facteur inductible par l'hypoxie approprié, en particulier le désidustat ou des sels pharmaceutiquement acceptables appropriés de celui-ci. L'invention concerne également des procédés de préparation de telles compositions. La présente invention concerne également le développement d'un composé thérapeutique pour le traitement de la toxicité induite par un rayonnement. Plus particulièrement, la présente invention concerne l'utilisation de désidustat ou de son sel pharmaceutiquement acceptable ou d'une composition pharmaceutique orale et parentérale associée pour le traitement de la toxicité induite par un rayonnement.

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