WO2026018268 - TREATMENT OF DIABETES AND DIABETES INDUCED CKD AND THE ASSOCIATED SYMPTOMS

National phase entry is expected:
Publication Number WO/2026/018268
Publication Date 22.01.2026
International Application No. PCT/IN2025/051043
International Filing Date 12.07.2025
Title **
[English] TREATMENT OF DIABETES AND DIABETES INDUCED CKD AND THE ASSOCIATED SYMPTOMS
[French] TRAITEMENT DU DIABÈTE ET DE LA NÉPHROPATHIE CHRONIQUE INDUITE PAR LE DIABÈTE ET DES SYMPTÔMES ASSOCIÉS
Applicants **
ZYDUS LIFESCIENCES LIMITED
Inventors
JOHARAPURKAR, Amit
KSHIRASAGAR, Samadhan
JAIN, Mukul
Priority Data
202421053555   13.07.2024   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting3160
EPO Filing, Examination, Granting27024
Japan Filing, Examination, Granting3042
South Korea Filing, Examination, Granting3959
USA Filing, Examination, Granting10540
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Total: 47,725
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Abstract[English] The present invention describes synergistic compositions and combinations comprising one or more prolyl hydroxylase inhibitors or pharmaceutically acceptable salts thereof and a SGLT2 inhibitors or pharmaceutically acceptable salts thereof for the treatment of diabetes and diabetes induced CKD and the associated symptoms like anemia. Specifically, the present invention provides synergistic composition and combination of compound of formula (Ia) or its pharmaceutically acceptable salts and a SGLT2 inhibitors or pharmaceutically acceptable salts thereof for the treatment of diabetes and diabetes induced CKD and the associated symptoms like anemia. The present invention also describes the preparation of such compositions and combinations.[French] La présente invention concerne des compositions et des combinaisons synergiques comprenant un ou plusieurs inhibiteurs de la prolyle hydroxylase ou leurs sels pharmaceutiquement acceptables et un inhibiteur du SGLT2 ou ses sels pharmaceutiquement acceptables pour le traitement du diabète et de la néphropathie chronique induite par le diabète et des symptômes associés, tels que l'anémie. Plus particulièrement, la présente invention concerne une composition synergique et une combinaison d'un composé de formule (Ia) ou de ses sels pharmaceutiquement acceptables et d'un inhibiteur du SGLT2 ou de ses sels pharmaceutiquement acceptable pour le traitement du diabète et de la néphropathie chronique induite par le diabète et des symptômes associés, tels que l'anémie. La présente invention concerne également la préparation de telles compositions et combinaisons.

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