WO2025134150 - BIPHENYL PYRIDINE RIGID COMPOUNDS WITH POLYCYCLIC HETEROCYCLES USEFUL AS DUAL IMMUNE CHECKPOINT INHIBITORS
National phase entry is expected:
Publication Number
WO/2025/134150
Publication Date
26.06.2025
International Application No.
PCT/IN2024/052405
International Filing Date
20.12.2024
Title **
[English]
BIPHENYL PYRIDINE RIGID COMPOUNDS WITH POLYCYCLIC HETEROCYCLES USEFUL AS DUAL IMMUNE CHECKPOINT INHIBITORS
[French]
COMPOSÉS RIGIDES DE BIPHÉNYLPYRIDINE AVEC HÉTÉROCYCLES POLYCYCLIQUES UTILES EN TANT QU'INHIBITEURS DE DOUBLE POINT DE CONTRÔLE IMMUNITAIRE
Applicants **
NATCO PHARMA LIMITED
Inventors
KOMPELLA, Amala
VEGICHERLA, Kameswara Rao
PEDDAKOTLA, Sagar Vijay Kumar
GUNTREDDI, Tirumaleswararao
JASTI, Lakshmi Prasanna
ALVALA, Mallika
BABBUR, Kiran Kumar
NANNAPANENI, Venkaiah Chowdary
Priority Data
202341088165
22.12.2023
IN
Application details
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International Searching Authority |
IP India
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3402 | |
| EPO | Filing, Examination, Granting | 20341 | |
| Japan | Filing, Examination, Granting | 2452 | |
| South Korea | Filing, Examination, Granting | 2712 | |
| USA | Filing, Examination, Granting | 7640 |
Total:
36,547
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Abstract[English]
This present invention relates to small molecules which are biphenyl pyridine rigid compounds with polycyclic heterocycles therapeutically useful as immune modulators These compounds disrupt the PD-1/PD-L1 checkpoint pathway and may also disrupt one or more related checkpoint pathways. These compounds are useful in treating, preventing or ameliorating disorders such as cancer or infections.[French]
La présente invention concerne de petites molécules qui sont des composés rigides de biphénylpyridine avec des hétérocycles polycycliques, utiles en thérapie en tant que modulateurs immunitaires. Ces composés perturbent la voie de contrôle PD-1/PD-L1 et peuvent également perturber une ou plusieurs voies de contrôle associées. Ces composés sont utiles dans le traitement, la prévention ou l'amélioration de troubles tels que le cancer ou les infections.