WO2024089702 - AN IMPROVED PROCESS FOR THE PREPARATION OF TUCATINIB AND ITS SALT & POLYMORPHS THEREOF

National phase entry is expected:
Publication Number WO/2024/089702
Publication Date 02.05.2024
International Application No. PCT/IN2023/050071
International Filing Date 23.01.2023
Title **
[English] AN IMPROVED PROCESS FOR THE PREPARATION OF TUCATINIB AND ITS SALT & POLYMORPHS THEREOF
[French] PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE TUCATINIB ET DE SON SEL ET DE SES POLYMORPHES
Applicants **
NATCO PHARMA LIMITED
Inventors
KONDURI, Srinivasa Krishna Murthy
GANGANAMONI, Srinivasulu
GUTALA, Phaneendra
BODDULA, Srinivas
KUSUMBA, Subhash
MADDULA, Laxmana Viswa Venkata Pavan Kumar
ANNADASU, Ankamanayudu
MUDDASANI, Pulla Reddy
NANNAPANENI, Venkaiah Chowdary
Priority Data
202241061499   28.10.2022   IN
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting1954
EPO Filing, Examination, Granting11600
Japan Filing, Examination, Granting2024
South Korea Filing, Examination, Granting1783
USA Filing, Examination, Granting6540
MasterCard Visa
Total: 23,901

The term for entry into the National Phase has expired. This quotation is for informational purposes only

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Abstract[English] The present invention relates to an improved process for the preparation of (N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine compound of formula-1 and its salt & polymorphs thereof which is represented by the following structural formula.[French] La présente invention concerne un procédé de préparation d'un composé de (N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-méthylphényl)-N6-(4,4-diméthyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine de formule 1 et ses sels et polymorphes qui est représenté par la formule structurelle suivante.

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