WO2026139906 - HUMANIZED ANTI-MESOTHELIN SCFVS

National phase entry is expected:
Publication Number WO/2026/139906
Publication Date 02.07.2026
International Application No. PCT/IB2025/063421
International Filing Date 23.12.2025
Title **
[English] HUMANIZED ANTI-MESOTHELIN SCFVS
[French] SCFV ANTI-MÉSOTHÉLINE HUMANISÉS
Applicants **
UNIVERSITY HEALTH NETWORK
Inventors
HIRANO, Naoto
OHASHI, Yota
LY, Dalam
SASO, Kayoko
MATSUNAGA, Yukiko
BURT, Brian
Priority Data
63/738,245   23.12.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting5553
EPO Filing, Examination, Granting104133
Japan Filing, Examination, Granting4981
South Korea Filing, Examination, Granting8335
USA Filing, Examination, Granting25190
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Total: 148,192
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Abstract[English] The disclosure provides scFv molecule that specifically bind mesothelin, chimeric antigen receptors that comprise antigen-binding domains comprising the scFv, nucleotides that encode the same, cells comprising the same, and methods of using the same in the treatment of cancer.[French] La divulgation fournit des molécules scFv se liant spécifiquement à la mésothéline, des récepteurs antigéniques chimériques comprenant des domaines de liaison à l'antigène comprenant les scFv, des nucléotides codant pour ceux-ci, des cellules comprenant ceux-ci, et des méthodes d'utilisation de ceux-ci dans le traitement du cancer.