WO2026133259 - RECOMBINANT YEAST HOST CELLS COMPRISING A HETEROLOGOUS ATP FUTILE CYCLE
National phase entry is expected:
Publication Number
WO/2026/133259
Publication Date
25.06.2026
International Application No.
PCT/IB2025/063193
International Filing Date
18.12.2025
Title **
[English]
RECOMBINANT YEAST HOST CELLS COMPRISING A HETEROLOGOUS ATP FUTILE CYCLE
[French]
CELLULES HÔTES DE LEVURE RECOMBINANTES COMPRENANT UN CYCLE FUTILE D'ATP HÉTÉROLOGUE
Applicants **
DANSTAR FERMENT AG
Inventors
WANG, Jian
FROEHLICH, Allan
HENNINGSEN, Brooks
BARRETT, Trisha
DELEAULT, Kristen
STONEHOUSE, Emily
VAN DIJKEN, Johannes Peter
Priority Data
63/736,111
19.12.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
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| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2876 | |
| EPO | Filing, Examination, Granting | 14532 | |
| Japan | Filing, Examination, Granting | 2448 | |
| South Korea | Filing, Examination, Granting | 2548 | |
| USA | Filing, Examination, Granting | 5590 |
Total:
27,994
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Abstract[English]
The present disclosure concerns recombinant yeast host cells for the production of one or more fermentation products. The recombinant yeast host cells of the present disclosure comprise at least one first genetic modification for providing a heterologous ATP futile cycle. The recombinant yeast host cells of the present disclosure also comprise at least one second 5 genetic modification in an engineered metabolic pathway for decreasing the production of the fermentation by-product.[French]
La présente divulgation concerne des cellules hôtes de levure recombinantes pour la production d'un ou de plusieurs produits de fermentation. Les cellules hôtes de levure recombinantes de la présente divulgation comprennent au moins une première modification génétique pour fournir un cycle futile d'ATP hétérologue. Les cellules hôtes de levure recombinantes de la présente divulgation comprennent également au moins une seconde modification génétique apportée à une voie métabolique modifiée pour diminuer la production du sous-produit de fermentation.