WO2026133209 - SOLID LIPID NANOPARTICLES AS ROBUST DRUG DELIVERY SYSTEMS
National phase entry is expected:
Publication Number
WO/2026/133209
Publication Date
25.06.2026
International Application No.
PCT/IB2025/063087
International Filing Date
17.12.2025
Title **
[English]
SOLID LIPID NANOPARTICLES AS ROBUST DRUG DELIVERY SYSTEMS
[French]
NANOPARTICULES LIPIDIQUES SOLIDES EN TANT QUE SYSTÈMES ROBUSTES D'ADMINISTRATION DE MÉDICAMENT
Applicants **
HUXLEY HEALTH INC.
Inventors
TRANT, John
HOSIE, William Charles
BANERJEE, Abhinandan
RAZMKHAH, Kasra
EGBUTA, Mary
BOLANDI, Behzad
Priority Data
63/734,866
17.12.2024
US
Application details
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International Searching Authority |
CIPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2268 | |
| EPO | Filing, Examination, Granting | 14392 | |
| Japan | Filing, Examination, Granting | 2392 | |
| South Korea | Filing, Examination, Granting | 2521 | |
| USA | Filing, Examination, Granting | 5340 |
Total:
26,913
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Abstract[English]
Disclosed is a process for the assembly solid lipid nanoparticles (SLNs) by a process that comprises: (a) combining (i) a therapeutic amount of one or psychedelics, (ii) a solid lipid at room temperature (25 °C) that can be composed of mono-, di, and tri-glycerides, (iii) a primary surfactant, (iv) a co-surfactant(s) (b) high-shear mixing said ingredients in a container to form a coarse-emulsion product, and (c) subjecting the coarse-emulsion through a microfluidic device to produce a solid lipid nanoparticle nanoemulsion containing a psychedelic(s).[French]
L'invention concerne un procédé pour l'assemblage de nanoparticules lipidiques solides (SLN) par un processus qui comprend les étapes suivantes : (a) combiner (i) une quantité thérapeutique d'un ou de plusieurs psychédéliques, (ii) un lipide solide à température ambiante (25 °C) qui peut être composé de monoglycérides, de diglycérides et de triglycérides, (iii) un tensioactif primaire, (iv) un ou plusieurs cotensioactifs, (b) procéder à un mélange à cisaillement élevé de ces ingrédients dans un récipient pour obtenir un produit sous forme d'émulsion grossière, et (c) faire passer l'émulsion grossière à travers un dispositif microfluidique afin de produire une nanoémulsion de nanoparticules lipidiques solides contenant un ou plusieurs psychédéliques.