WO2026126144 - XANOMELINE COMBINATIONS FOR TREATING NEUROLOGICAL DISORDERS

National phase entry is expected:
Publication Number WO/2026/126144
Publication Date 18.06.2026
International Application No. PCT/IB2025/062744
International Filing Date 11.12.2025
Title **
[English] XANOMELINE COMBINATIONS FOR TREATING NEUROLOGICAL DISORDERS
[French] ASSOCIATIONS DE XANOMÉLINE POUR LE TRAITEMENT DE TROUBLES NEUROLOGIQUES
Applicants **
SYREMIS THERAPEUTICS LTD.
Inventors
KAGAN, Elena
Priority Data
63/733,023   12.12.2024   US
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Quotation for National Phase entry

Country StagesTotal
China Filing, Examination, Granting2959
EPO Filing, Examination, Granting11803
Japan Filing, Examination, Granting2170
South Korea Filing, Examination, Granting2060
USA Filing, Examination, Granting8040
MasterCard Visa
Total: 27,032
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Abstract[English] The present invention relates to new compositions containing xanomeline and a CYP2D6 inhibitor. The present invention also relate to the use of xanomeline and a CYP2D6 inhibitor to increase a subject's xanomeline plasma concentrations. The present invention also relate to the use of xanomeline and a CYP2D6 inhibitor for treating disease including neurological disorders, such as psychosis and schizophrenia.[French] La présente invention concerne de nouvelles compositions contenant de la xanoméline et un inhibiteur du CYP2D6. La présente invention concerne également l'utilisation de la xanoméline et d'un inhibiteur du CYP2D6 pour augmenter les concentrations plasmatiques de xanoméline chez un sujet. La présente invention concerne également l'utilisation de la xanoméline et d'un inhibiteur du CYP2D6 pour le traitement de maladies comprenant des troubles neurologiques, tels que la psychose et la schizophrénie.

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