WO2026094019 - METHODS OF PREDICTING TREATMENT RESPONSES IN MULTIPLE MYELOMA USING SPATIAL SIGNATURES
National phase entry is expected:
Publication Number
WO/2026/094019
Publication Date
07.05.2026
International Application No.
PCT/IB2025/061235
International Filing Date
04.11.2025
Title **
[English]
METHODS OF PREDICTING TREATMENT RESPONSES IN MULTIPLE MYELOMA USING SPATIAL SIGNATURES
[French]
PROCÉDÉS DE PRÉDICTION DE RÉPONSES À UN TRAITEMENT CONTRE UN MYÉLOME MULTIPLE AU MOYEN DE SIGNATURES SPATIALES
Applicants **
DANA-FARBER CANCER INSTITUTE, INC
Inventors
KONISHI, Yoshinobu
GHOBRIAL, Irene
CORDAS DOS SANTOS, David
VERGA, Jacopo Umberto
Priority Data
63/716,000
04.11.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
| Pages for Publication | * |
| Number of Pages with Drawings | * |
| Pages of Specification | * |
| * | |
| Number of Office Actions | * |
| * | |
International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
* |
| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
* |
| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
|
* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2719 | |
| EPO | Filing, Examination, Granting | 14469 | |
| Japan | Filing, Examination, Granting | 2454 | |
| South Korea | Filing, Examination, Granting | 2607 | |
| USA | Filing, Examination, Granting | 7340 |
Total:
29,589
Contact Us
Abstract[English]
The present disclosure relates to computer-implemented methods for classifying cell neighborhoods in a bone marrow sample obtained from a subject suffering from multiple myeloma (MM) and for defining significant cell neighborhoods in that sample that are associated with treatment outcomes in subjects with MM who receive a T cell-redirecting therapy. Image processing systems that can be used to analyze bone marrow samples and identify cell neighborhoods are also provided. Moreover, methods for predicting a treatment response to a T cell-redirecting therapy in a subject suffering from MM are disclosed.[French]
La présente divulgation concerne des procédés mis en œuvre par ordinateur permettant de classifier des voisinages de cellules dans un échantillon de moelle osseuse obtenu auprès d'un sujet souffrant d'un myélome multiple (MM) et de définir des voisinages de cellules significatifs dans cet échantillon, qui sont associés à des résultats de traitement chez des sujets atteints de MM qui reçoivent une thérapie de redirection de lymphocytes T. La divulgation concerne également des systèmes de traitement d'image qui peuvent être utilisés pour analyser des échantillons de moelle osseuse et identifier des voisinages de cellule. La divulgation concerne en outre des procédés de prédiction d'une réponse au traitement pour une thérapie de redirection de lymphocytes T chez un sujet souffrant de MM.