WO2026062579 - COMPOSITIONS AND METHODS FOR PROTEIN DELIVERY TO CELLS
National phase entry is expected:
Publication Number
WO/2026/062579
Publication Date
26.03.2026
International Application No.
PCT/IB2025/059449
International Filing Date
19.09.2025
Title **
[English]
COMPOSITIONS AND METHODS FOR PROTEIN DELIVERY TO CELLS
[French]
COMPOSITIONS ET PROCÉDÉS DE DISTRIBUTION DE PROTÉINES À DES CELLULES
Applicants **
COMED THERAPEUTICS LTD.
Inventors
ÖZTÜRK, Cenk
HEKIM, Suleyman Nezih
Priority Data
63/696,777
19.09.2024
US
Application details
| Total Number of Claims/PCT | * |
| Number of Independent Claims | * |
| Number of Priorities | * |
| Number of Multi-Dependent Claims | * |
| Number of Drawings | * |
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| Number of Pages with Drawings | * |
| Pages of Specification | * |
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International Searching Authority |
EPO
* |
| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
* |
| Type of Assignment |
The Standard Agent's Assignment
* |
| Applicant's Legal Status |
Legal Entity
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| * | |
| * | |
| * | |
| * | |
| * | |
| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
* |
| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 3321 | |
| EPO | Filing, Examination, Granting | 23775 | |
| Japan | Filing, Examination, Granting | 3018 | |
| South Korea | Filing, Examination, Granting | 3548 | |
| USA | Filing, Examination, Granting | 11790 |
Total:
45,452
Abstract[English]
Provided are molecular hooks that are capable of tethering a protein of interest to a high-density lipoprotein (HDL) molecule. Also provided are methods of intracellular protein delivery to cells and organisms using the molecular hooks of the present disclosure. Such methods provide several advantages including the ability to intracellularly deliver the protein of interest to tissues behind the blood-brain barrier, and not requiring extreme cold temperatures for storage or transport.[French]
L'invention concerne des crochets moléculaires qui sont capables de fixer une protéine d'intérêt à une molécule de lipoprotéine de haute densité (HDL). L'invention concerne également des procédés d'administration intracellulaire de protéines à des cellules et des organismes à l'aide des crochets moléculaires de la présente divulgation. De tels procédés fournissent plusieurs avantages, notamment la capacité à délivrer de manière intracellulaire la protéine d'intérêt à des tissus derrière la barrière hémato-encéphalique, et le fait de ne pas nécessiter de températures froides extrêmes pour le stockage ou le transport.