WO2026033435 - METHODS OF DETECTING, DIAGNOSING, CLASSIFYING AND/OR MONITORING CANCERS USING CELL-FREE DNA AND KITS OR DEVICES IMPLEMENTING THE SAME
National phase entry is expected:
Publication Number
WO/2026/033435
Publication Date
12.02.2026
International Application No.
PCT/IB2025/058005
International Filing Date
06.08.2025
Title **
[English]
METHODS OF DETECTING, DIAGNOSING, CLASSIFYING AND/OR MONITORING CANCERS USING CELL-FREE DNA AND KITS OR DEVICES IMPLEMENTING THE SAME
[French]
PROCÉDÉS DE DÉTECTION, DE DIAGNOSTIC, DE CLASSIFICATION ET/OU DE SURVEILLANCE DE CANCERS À L'AIDE D'ADN ACELLULAIRE ET KITS OU DISPOSITIFS LES METTANT EN ŒUVRE
Applicants **
DANA-FARBER CANCER INSTITUTE, INC.
Inventors
LONG, Henry W.
CEJAS, Paloma
BELLMUNT, Joaquim
Priority Data
63/679,845
06.08.2024
US
Application details
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International Searching Authority |
EPO
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| Recordal of a Change of the Applicant's Name/Address |
Change of Applicant's Name and Address
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| Type of Assignment |
The Standard Agent's Assignment
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| Applicant's Legal Status |
Legal Entity
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| Entry into National Phase under |
Chapter I
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| Patent Delivery |
Send the Letters Patent by Courier
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| Translation |
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* The data is based on automatic recognition. Please verify and amend if necessary.
** IP-Coster compiles data from publicly available sources. If this data includes your personal information, you can contact us to request its removal.
Quotation for National Phase entry
| Country | Stages | Total | |
|---|---|---|---|
| China | Filing, Examination, Granting | 2909 | |
| EPO | Filing, Examination, Granting | 17270 | |
| Japan | Filing, Examination, Granting | 2610 | |
| South Korea | Filing, Examination, Granting | 2915 | |
| USA | Filing, Examination, Granting | 7140 |
Total:
32,844
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Abstract[English]
Provided herein are methods of detecting, diagnosing, classifying and/or monitoring cancer in a subject by isolating and enriching cell-free, chromatin-associated DNA and performing quantitative PCR (qPCR) to detect one or more nucleotide sequences associated with the presence of cancer. Also provided are methods of detecting, diagnosing, classifying and/or monitoring bladder cancer using specific gene regulatory regions and associated genes disclosed herein. Kits or devices implementing the same are also provided.[French]
L'invention concerne des procédés de détection, de diagnostic, de classification et/ou de surveillance du cancer chez un sujet par isolement et enrichissement de l'ADN acellulaire associé à la chromatine, et par réalisation d'une PCR quantitative (qPCR) pour détecter une ou plusieurs séquences nucléotidiques associées à la présence d'un cancer. L'invention concerne également des procédés de détection, de diagnostic, de classification et/ou de surveillance du cancer de la vessie à l'aide de régions régulatrices de gènes spécifiques et de gènes associés divulgués dans la description. L'invention concerne également des kits ou des dispositifs les mettant en œuvre.